| Literature DB >> 7097301 |
Abstract
A study of 206 patients with multiple sclerosis in the north-east of England and their families shows no evidence of monogenic involvement in the disorder. Much more likely is a multifactorial etiology in which the genetic component is polygenic. On this model the heritability is calculated at 52.1% or 40.9% if age variation in incidence is allowed for. The genetic component is present but no more then moderate in extent.Entities:
Mesh：
Year: 1982 PMID： 7097301 DOI： 10.1016/0022-510x(82)90189-7
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181