Literature DB >> 7097254

An electron microscopic demonstration of immune complexes of hepatitis B e-antigen using colloid gold as a marker.

L M Stannard, M Lennon, M Hodgkiss, H Smuts.   

Abstract

Immune complexes of the hepatitis B e-antigen (HBeAg) could be labeled and thus visually identified in the electron microscope by using antibody to HBeAg (anti-HBe) tagged with colloidal gold particles. Circulating immune complexes of HBeAg were detected in sera from patients with acute hepatitis B infections as well as from asymptomatic carriers of hepatitis B surface antigens (HBsAg). Sera positive for rheumatoid factor frequently contained mixed aggregates in which immune complexes of HBsAg were closely bound to immune complexes of HBeAg.

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Year:  1982        PMID： 7097254     DOI： 10.1002/jmv.1890090303

Source DB:  PubMed          Journal:  J Med Virol        ISSN： 0146-6615            Impact factor:   2.327


  4 in total

Review 1.  Applications of immunogold labelling in animal and plant virology.

Authors:  S Patterson; B J Verduin
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574

2.  Electron microscopic identification of rotavirus group antigen with gold-labelled monoclonal IgG.

Authors:  M L Martin; E L Palmer
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

3.  Hepatitis B virus associated membranous glomerulonephritis.

Authors:  J Wiggelinkhuizen; C Sinclair-Smith; L M Stannard; H Smuts
Journal:  Arch Dis Child       Date:  1983-07       Impact factor: 3.791

4.  Development of protein A-gold immunoelectron microscopy for detection of bovine coronavirus in calves: comparison with ELISA and direct immunofluorescence of nasal epithelial cells.

Authors:  R A Heckert; L J Saif; G W Myers
Journal:  Vet Microbiol       Date:  1989-03       Impact factor: 3.293
  4 in total

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