Literature DB >> 7097160

Elicitation of delayed-type hypersensitivity to phosphorylcholine by monoclonal anti-idiotypic antibodies in an allogeneic environment.

B Arnold, R Wallich, G J Hämmerling.   

Abstract

Delayed-type hypersensitivity (DTH) to phosphorylcholine (PC) could be elicited by mixtures of monoclonal anti-idiotypic antibodies. Using this system in DTH transfers, the question was asked of whether anti-idiotypic antibodies could elicit antigen induced DTH in H-2-incompatible mice. Transfer of PC-activated BALB/c lymph node cells into BALB.K mice and subsequent elicitation with anti-idiotypic antibodies resulted in a positive DTH response. In contrast, elicitation with the antigen PC showed the expected H-2 restriction.

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Year:  1982        PMID： 7097160      PMCID： PMC2186770          DOI： 10.1084/jem.156.2.670

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  9 in total

1.  The chemical composition of pneumococcal C-polysaccharide.

Authors:  T Y LIU; E C GOTSCHLICH
Journal:  J Biol Chem       Date:  1963-06       Impact factor: 5.157

2.  Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

Authors:  R M Zinkernagel; P C Doherty
Journal:  Nature       Date:  1974-04-19       Impact factor: 49.962

3.  Affinity labeling of a phosphorylcholine binding mouse myeloma protein.

Authors:  B Chesebro; H Metzger
Journal:  Biochemistry       Date:  1972-02-29       Impact factor: 3.162

Review 4.  Expression and function of idiotypes of lymphocytes.

Authors:  K Eichmann
Journal:  Adv Immunol       Date:  1978       Impact factor: 3.543

5.  A radioisotopic method to measure delayed type hypersensitivity in the mouse. I. Studies in sensitized and normal mice.

Authors:  M A Vadas; J F Miller; J Gamble; A Whitelaw
Journal:  Int Arch Allergy Appl Immunol       Date:  1975

6.  Evidence for the endogenous production of T cell receptors bearing idiotypic determinants.

Authors:  M H Julius; H Cosenza; A A Augustin
Journal:  Eur J Immunol       Date:  1978-07       Impact factor: 5.532

7.  Antigen- and receptor-driven regulatory mechanisms. III. Induction of delayed type hypersensitivity to azobenzenearsonate with anti-cross-reactive idiotypic antibodies.

Authors:  M S Sy; A R Brown; B Benacerraf; M I Greene
Journal:  J Exp Med       Date:  1980-04-01       Impact factor: 14.307

8.  Elicitation of delayed-type hypersensitivity responses to poly(L-Tyr,LGlu)-poly(DLAla)--poly(LLys) by anti-idiotypic antibodies.

Authors:  G Strassmann; R Lifshitz; E Mozes
Journal:  J Exp Med       Date:  1980-11-01       Impact factor: 14.307

9.  Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody.

Authors:  W R Thomas; G Morahan; I D Walker; J F Miller
Journal:  J Exp Med       Date:  1981-03-01       Impact factor: 14.307
  9 in total
  2 in total

1.  Parasite exposure elicits a preferential T-cell response involved in protective immunity against Eimeria species in chickens primed by an internal-image anti-idiotypic antibody.

Authors:  B S Bhogal; E B Jacobson; H Y Tse; D M Schmatz; O J Ravino
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

2.  I-J determinants as restriction and activation signals.

Authors:  A Lowy; A Tominaga; M I Greene
Journal:  Surv Immunol Res       Date:  1983
  2 in total

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