Literature DB >> 709470

[Thalassemia in French-speaking Quebec residents].

L Desjardins, C Rousseau, J M Duplain, J P Valet, P Auger.   

Abstract

Eighty-five cases of beta-thalassemia minor were found between January 1975 and November 1977 in 18 families of French-speaking Quebeckers without Mediterranean ancestry. Most of the families had settled in Quebec more than 200 years ago, largely in Portneuf county. This is the first report of such a number of cases of beta-thalassemia in this population. Thus, beta-thalassemia minor is a relatively common condition in Quebec and must be considered in cases of microcytic anemia without evidence of iron deficiency. The hematologic findings were similar to those reported in the past in other populations. Two cases of delta beta-thalassemia minor (in sisters) are also reported; this is the first report of such cases in French Canadians.

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Mesh:

Year:  1978        PMID: 709470      PMCID: PMC1818757     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  6 in total

1.  [THALASSEMIA IN QUEBEC].

Authors:  E RIOUX; J M DELAGE
Journal:  Union Med Can       Date:  1964-09

2.  Estimation of small percentages of foetal haemoglobin.

Authors:  K BETKE; H R MARTI; I SCHLICHT
Journal:  Nature       Date:  1959-12-12       Impact factor: 49.962

3.  Haematological data in 312 cases of -thalassaemia trait in Thailand.

Authors:  P Pootrakul; P Wasi; S Na-Nakorn
Journal:  Br J Haematol       Date:  1973-06       Impact factor: 6.998

4.  Glycerol lysis time as a screening test for erythrocyte disorders.

Authors:  E L Gottfried; N A Robertson
Journal:  J Lab Clin Med       Date:  1974-02

5.  Thalassemia in Canadians.

Authors:  D Dauphinee; G R Langley
Journal:  Can Med Assoc J       Date:  1967-02-11       Impact factor: 8.262

6.  Thalassaemia in the British.

Authors:  H H Knox-Macaulay; D J Weatherall; J B Clegg; M E Pembrey
Journal:  Br Med J       Date:  1973-07-21
  6 in total
  2 in total

1.  Beta-thalassemia disease prevention: genetic medicine applied.

Authors:  C R Scriver; M Bardanis; L Cartier; C L Clow; G A Lancaster; J T Ostrowsky
Journal:  Am J Hum Genet       Date:  1984-09       Impact factor: 11.025

2.  Beta-thalassemia genes in French-Canadians: haplotype and mutation analysis of Portneuf chromosomes.

Authors:  F Kaplan; G Kokotsis; M DeBraekeleer; K Morgan; C R Scriver
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

  2 in total

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