Literature DB >> 7094661

Induced resistance in leukaemia L1210 to adriamycin and its cross-resistance to vincristine and bouvardin.

M P Chitnis, S S Joshi, R P Gude, R S Menon.   

Abstract

The induction of complete resistance to adriamycin in L1210 leukemia was accomplished after 10 transplant generations. The adriamycin-resistant subline showed cross-resistance to vincristine and bouvardin. It was sensitive to methotrexate; this was observed by a 50% increase in life span compared to the life span of untreated control animals.

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Year:  1982        PMID： 7094661     DOI： 10.1159/000238078

Source DB:  PubMed          Journal:  Chemotherapy        ISSN： 0009-3157            Impact factor:   2.544


  4 in total

1.  CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set.

Authors:  William C Reinhold; Margot Sunshine; Hongfang Liu; Sudhir Varma; Kurt W Kohn; Joel Morris; James Doroshow; Yves Pommier
Journal:  Cancer Res       Date:  2012-07-15       Impact factor: 12.701

Review 2.  Tumour cell resistance to anthracyclines--a review.

Authors:  S Kaye; S Merry
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

3.  Doxorubicin cellular pharmacokinetics and DNA breakage in a multi-drug resistant B16 melanoma cell line.

Authors:  R Supino; M Mariani; G Capranico; A Colombo; G Parmiani
Journal:  Br J Cancer       Date:  1988-02       Impact factor: 7.640

4.  Cross-resistance to cytotoxic drugs in human glioma cell lines in culture.

Authors:  S Merry; S B Kaye; R I Freshney
Journal:  Br J Cancer       Date:  1984-12       Impact factor: 7.640
  4 in total

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