Literature DB >> 7093203

Complete amino acid sequence of human brain calmodulin.

T Sasagawa, L H Ericsson, K A Walsh, W E Schreiber, E H Fischer, K Titani.   

Abstract

The complete amino acid sequence of calmodulin from human brain has been determined by using peptides derived from digests with trypsin. Staphylococcus aureus V8 protease, and cyanogen bromide. The peptides were purified by means of reversed-phase high-performance liquid chromatography and analyzed with a sequenator. The protein contains 148 amino acid residues and has a molecular weight of 16792. As in other calmodulins, the amino-terminal residue of the protein is blocked by an acetyl group, and a trimethyllysine residue is located at position 115. The only difference between this sequence and those fully determined in other species is the assignment of amide groups.

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Year:  1982        PMID： 7093203     DOI： 10.1021/bi00539a041

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  18 in total

1.  Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences.

Authors:  N D Moncrief; R H Kretsinger; M Goodman
Journal:  J Mol Evol       Date:  1990-06       Impact factor: 2.395

2.  Amino Acid sequence of a novel calmodulin from the unicellular alga chlamydomonas.

Authors:  T J Lukas; M E Wiggins; D M Watterson
Journal:  Plant Physiol       Date:  1985-07       Impact factor: 8.340

3.  Isolation and sequence analysis of a cDNA clone for a carrot calcium-dependent protein kinase: homology to calcium/calmodulin-dependent protein kinases and to calmodulin.

Authors:  K L Suen; J H Choi
Journal:  Plant Mol Biol       Date:  1991-10       Impact factor: 4.076

4.  Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.

Authors:  J P Salier; M Diarra-Mehrpour; R Sesboue; J Bourguignon; R Benarous; I Ohkubo; S Kurachi; K Kurachi; J P Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function.

Authors:  J C Loftus; E F Plow; A L Frelinger; S E D'Souza; D Dixon; J Lacy; J Sorge; M H Ginsberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

6.  Stabilization of the long central helix of troponin C by intrahelical salt bridges between charged amino acid side chains.

Authors:  M Sundaralingam; W Drendel; M Greaser
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

7.  Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences.

Authors:  J P Stein; R P Munjaal; L Lagace; E C Lai; B W O'Malley; A R Means
Journal:  Proc Natl Acad Sci U S A       Date:  1983-11       Impact factor: 11.205

8.  Isolation and characterization of calmodulin genes from Xenopus laevis.

Authors:  Y H Chien; I B Dawid
Journal:  Mol Cell Biol       Date:  1984-03       Impact factor: 4.272

9.  Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins.

Authors:  P Baum; C Furlong; B Byers
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

10.  Calcium-dependent protease of the cyanobacterium Anabaena: molecular cloning and expression of the gene in Escherichia coli, sequencing and site-directed mutagenesis.

Authors:  I Maldener; W Lockau; Y P Cai; C P Wolk
Journal:  Mol Gen Genet       Date:  1991-01
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