Literature DB >> 7092842

Deoxycholic acid degradation by a Pseudomonas species. Acidic intermediates from the initial part of the catabolic pathway.

R A Leppik.   

Abstract

The microbial catabolism of deoxycholic acid by a Pseudomonas species was studied, and three acidic products were isolated as their methyl esters. Evidence is presented that the compounds are methyl 3 alpha,12 alpha-dihydroxy-23,24-dinor-5 beta-cholan-22-oate, methyl 12 alpha-hydroxy-3-oxo-5 beta-cholan-24-oate and methyl 12 alpha-hydroxy-3-oxo-23,24-dinor-5 beta-cholan-22-oate.

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Year:  1982        PMID： 7092842      PMCID： PMC1158171          DOI： 10.1042/bj2020747

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  The anaerobic side-chain cleavage of bile acids by Escherichia coli isolated from human faeces [proceedings].

Authors:  M E Tenneson; R W Owen; A N Mason
Journal:  Biochem Soc Trans       Date:  1977       Impact factor: 5.407

Review 2.  Microbiological transformation of bile acids.

Authors:  S Hayakawa
Journal:  Adv Lipid Res       Date:  1973

3.  The enzymatic transformation of cholic acid by the culture Mycobacterium mucosum 1210.

Authors:  L O Severina; I V Torgov; G K Skrjabin; N S Wulfson; V I Zaretskii; I B Papernaja
Journal:  Tetrahedron       Date:  1969-02       Impact factor: 2.457

4.  The transformation of desoxycholic acid by the culture Mycobacterium mucosum 1210.

Authors:  L O Severina; I V Torgov; G K Skrjabin; V I Zaretskii; N S Wulfson; I B Papernaja
Journal:  Tetrahedron       Date:  1969-12       Impact factor: 2.457

5.  Transformation of cholic acid by the culture Mycobacterium N 1210.

Authors:  L O Severina; I V Torgov; G K Skrjabin; N S Wulfson; V I Zaretskii; I B Papernaja
Journal:  Tetrahedron       Date:  1968-03       Impact factor: 2.457

6.  The degradation of cholic acid and deoxycholic acid by Bacteroides species under strict anaerobic conditions.

Authors:  R W Owen; R F Bilton; M E Tenneson
Journal:  Biochem Soc Trans       Date:  1977       Impact factor: 5.407

7.  New dehydroxylation reaction observed in the microbiological degradation pathway of cholic acid.

Authors:  S Hayakawa; Y Kanematsu; T Fujiwara
Journal:  Nature       Date:  1967-04-29       Impact factor: 49.962

8.  The degradation of cholic acid by Pseudomonas sp. N.C.I.B. 10590.

Authors:  M E Tenneson; J D Baty; R F Bilton; A N Mason
Journal:  Biochem J       Date:  1979-12-15       Impact factor: 3.857
  8 in total
  5 in total

1.  Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism.

Authors:  Suzanne T Thomas; Brian C VanderVen; David R Sherman; David G Russell; Nicole S Sampson
Journal:  J Biol Chem       Date:  2011-11-01       Impact factor: 5.157

2.  Pseudomonas mutant strains that accumulate androstane and seco-androstane intermediates from bile acids.

Authors:  R A Leppik; D J Sinden
Journal:  Biochem J       Date:  1987-04-01       Impact factor: 3.857

3.  Deoxycholic acid degradation by a Pseudomonas sp. Acidic intermediates with A-ring unsaturation.

Authors:  R A Leppik
Journal:  Biochem J       Date:  1983-03-15       Impact factor: 3.857

4.  Aerobic catabolism of bile acids.

Authors:  R A Leppik; R J Park; M G Smith
Journal:  Appl Environ Microbiol       Date:  1982-10       Impact factor: 4.792

5.  Effect of restricted aeration on catabolism of cholic acid by two Pseudomonas species.

Authors:  M G Smith; R J Park
Journal:  Appl Environ Microbiol       Date:  1984-07       Impact factor: 4.792
  5 in total

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