Literature DB >> 7092797

Identification of eleven human hemoglobin variants by high-performance liquid chromatography: additional data on functional properties and clinical expression.

W A Schroeder, J B Shelton, J R Shelton, D Powars, S Friedman, J Baker, J Z Finklestein, B Miller, C S Johnson, J R Sharpsteen, L Sieger, E Kawaoka.   

Abstract

Eleven abnormal hemoglobins were detected in the course of cord blood screening or in the evaluation of evident hematological problems in individual cases. Identification of the variant in each case was done by high-performance liquid chromatography (HPLC); HPLC provides a rapid, sensitive means for the examination of abnormal hemoglobins. Some of the 11 variants that were identified have been described repeatedly and are included to provide information on the HPLC behavior of tryptic peptides. Others are much rarer. Additional information is provided about the hematological and clinical expression as well as ethnic and geographical distribution of the abnormal hemoglobin.

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Year:  1982        PMID： 7092797     DOI： 10.1007/BF00484942

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  36 in total

1.  Hemoglobin Fannin-Lubbock [alpha2 beta 2 119 (GH2) Gly replaced by Asp]. A new hemoglobin variant at the alpha1 beta 1 contact.

Authors:  W F Moo-Penn; K C Bechtel; M H Johnson; D L Jue; B L Therrell; B Y Morrison; R M Schmidt
Journal:  Biochim Biophys Acta       Date:  1976-12-22

2.  Chemical heterogeneity of haemoglobin O.

Authors:  C BAGLIONI; H LEHMANN
Journal:  Nature       Date:  1962-10-20       Impact factor: 49.962

3.  [New hemoglobin anomaly in a chaild with hemolytic anemia].

Authors:  J BERNARD; G SCHAPIRA; J C DREYFUS; G MATHE; J ROSA
Journal:  Sang       Date:  1958

4.  Structural characterization of hemoglobin-N-Seattle.

Authors:  R T Jones; B Brimhall; E R Huehns; A G Motulsky
Journal:  Biochim Biophys Acta       Date:  1968-02-19

5.  Haemoglobin Rampa: Alpha 95 Pro--Ser.

Authors:  W W de Jong; L F Bernini; P Meera Khan
Journal:  Biochim Biophys Acta       Date:  1971-04-27

6.  Hemoglobin variants and methods used for their characterization during 7 years of screening at the Center for Disease Control.

Authors:  W F Moo-Penn; D L Jue; M H Johnson; K C Bechtel; L C Patchen
Journal:  Hemoglobin       Date:  1980       Impact factor: 0.849

7.  Hemoglobin Pasadena,alpha 2 beta 275(E19)Leu leads to Arg. Identification by high performance liquid chromatography of a new unstable variant with increased oxygen affinity.

Authors:  C S Johnson; D Moyes; W A Schroeder; J B Shelton; J R Shelton; E Beutler
Journal:  Biochim Biophys Acta       Date:  1980-06-26

8.  Hemoglobin Richmond, a human hemoglobin which forms asymmetric hybrids with other hemoglobins.

Authors:  G D Efremov; T H Huisman; L L Smith; J B Wilson; J L Kitchens; R N Wrightstone; H R Adams
Journal:  J Biol Chem       Date:  1969-11-25       Impact factor: 5.157

9.  The oxygen affinity of haemoglobin Hammersmith.

Authors:  A May; E R Huehns
Journal:  Br J Haematol       Date:  1975-06       Impact factor: 6.998

10.  Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.

Authors:  M W Hunkapiller; L E Hood
Journal:  Biochemistry       Date:  1978-05-30       Impact factor: 3.162
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  3 in total

1.  An unusual phenotypic expression of Hb-Leiden.

Authors:  W A Schroeder; D Powars; J B Shelton; J R Shelton; J B Wilson; T H Huisman; A A Bedros
Journal:  Biochem Genet       Date:  1982-12       Impact factor: 1.890

2.  Preparation and characterization of a pentaammineruthenium(III) derivative of horse heart ferricytochrome c.

Authors:  K M Yocom; J B Shelton; J R Shelton; W A Schroeder; G Worosila; S S Isied; E Bordignon; H B Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

3.  Oxidant damage of the lipids and proteins of the erythrocyte membranes in unstable hemoglobin disease. Evidence for the role of lipid peroxidation.

Authors:  T P Flynn; D W Allen; G J Johnson; J G White
Journal:  J Clin Invest       Date:  1983-05       Impact factor: 14.808
  3 in total

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