Literature DB >> 7092699

Effect of nicotinic acid on cochlear blood flow.

E Hultcrantz, M Hillerdal, C Angelborg.   

Abstract

Effects of nicotinic acid on cochlear blood flow were studied in rats by the microsphere method. One measurement was performed before drug administration and the second after i.v. injection of the nicotinic acid 25 mg/kg body weight. No measurable effect on cochlear blood flow was observed in normal animals. In one group of animals the cervical sympathetic trunks were cut and the distal part on one side was electrically stimulated during the measurements. On the unstimulated side the cochlear blood flow was significantly higher than in intact animals, but uninfluenced by nicotinic acid. On the sympathetically stimulated side a significant increase of the cochlear blood flow occurred after nicotinic acid administration.

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Year:  1982        PMID: 7092699     DOI: 10.1007/BF00453622

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN: 0302-9530


  9 in total

Review 1.  Local regulation of adrenergic neurotransmission.

Authors:  T C Westfall
Journal:  Physiol Rev       Date:  1977-10       Impact factor: 37.312

Review 2.  Clinical pharmacology and pharmacokinetics of nicotinic acid.

Authors:  M Weiner
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3.  Cochlear blood flow in response to vasodilating drugs and some related agents.

Authors:  F Suga; J B Snow
Journal:  Laryngoscope       Date:  1969-11       Impact factor: 3.325

4.  Pharmacology of perilymph production.

Authors:  B Kellerhals
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1974       Impact factor: 1.538

Review 5.  Prejunctional receptors modulating autonomic neuroeffector transmission.

Authors:  M J Rand; H Majewski; I C Medgett; M W McCulloch; D F Story
Journal:  Circ Res       Date:  1980-06       Impact factor: 17.367

6.  Early effects of cervical sympathetic stimulation on cerebral, ocular and cochlear blood flow.

Authors:  M Beausang-Linder; E Hultcrantz
Journal:  Acta Physiol Scand       Date:  1980-08

7.  Effects of CO2 inhalation on cochlear blood circulation.

Authors:  E Hultcrantz; H C Larsen; C Angelborg
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1980       Impact factor: 1.538

8.  Dissociation of the effects of nicotinic acid on vasodilatation and lipolysis by a prostaglandin synthesis inhibitor, indomethacin, in man.

Authors:  L Kaijser; B Eklund; A G Olsson; L A Carlson
Journal:  Med Biol       Date:  1979-04

9.  The cochlear blood flow.

Authors:  C Angelborg; E Hultcrantz; B Agerup
Journal:  Acta Otolaryngol       Date:  1977 Jan-Feb       Impact factor: 1.494

  9 in total
  5 in total

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Journal:  Occup Environ Med       Date:  2004-04       Impact factor: 4.402

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Journal:  Eur Arch Otorhinolaryngol       Date:  1993       Impact factor: 2.503

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Journal:  Arch Otorhinolaryngol       Date:  1984

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  5 in total

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