[Alexander's disease (author's transl)].

A report on clinical course and morphological findings in a case of Alexander's disease is given in a boy aged 4 year and 6 months. The disease started in the second month with progressive retardation. At the age of 13 months, a ventriculo-peritoneal shunt was performed because of dilatation of ventricles. Death occurred due to cerebral dysfunction. Microscopic investigation showed a considerable demyelination and the presence of numerous Rosenthal fibers. The results are compared with observations in the literature of Alexander's disease during early infancy.