Literature DB >> 7089996

Cytochrome P-450 dependent monooxygenase activity in rat nasal epithelial membranes.

W M Hadley, A R Dahl.   

Abstract

Cytochrome P-450 was found in nasal epithelial membranes (NEM) of the rat. The quantity was 12% that of liver on a per mg of microsomal protein basis and 1.6 times that of lung on the same basis. Metabolism of p-nitroanisole was faster by microsomes from NEM than by microsomes from liver or lungs while the metabolism rate of aniline by microsomes from NEM was between that of microsomes from liver and lung.

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Year:  1982        PMID： 7089996     DOI： 10.1016/0378-4274(82)90240-5

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  10 in total

1.  NADPH: cytochrome P-450 reductase in olfactory epithelium. Relevance to cytochrome P-450-dependent reactions.

Authors:  C J Reed; E A Lock; F De Matteis
Journal:  Biochem J       Date:  1986-12-01       Impact factor: 3.857

2.  Response of the macaque nasal epithelium to ambient levels of ozone. A morphologic and morphometric study of the transitional and respiratory epithelium.

Authors:  J R Harkema; C G Plopper; D M Hyde; J A St George; D W Wilson; D L Dungworth
Journal:  Am J Pathol       Date:  1987-07       Impact factor: 4.307

3.  The characterization of glutathione S-transferases from rat olfactory epithelium.

Authors:  K K Banger; E A Lock; C J Reed
Journal:  Biochem J       Date:  1993-02-15       Impact factor: 3.857

4.  Metabolism of chlorobenzene in the mucosa of the murine respiratory tract.

Authors:  E Brittebo; I Brandt
Journal:  Lung       Date:  1984       Impact factor: 2.584

5.  Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa.

Authors:  Varsha Dhamankar; Mahfoud Assem; Maureen D Donovan
Journal:  Inhal Toxicol       Date:  2015-11-16       Impact factor: 2.724

6.  Isolation and long-term culture of rat, rabbit, and human nasal turbinate epithelial cells.

Authors:  V E Steele; J T Arnold
Journal:  In Vitro Cell Dev Biol       Date:  1985-12

Review 7.  Biotransformation enzymes in the rodent nasal mucosa: the value of a histochemical approach.

Authors:  M S Bogdanffy
Journal:  Environ Health Perspect       Date:  1990-04       Impact factor: 9.031

Review 8.  Nonneoplastic changes in the olfactory epithelium--experimental studies.

Authors:  B A Gaskell
Journal:  Environ Health Perspect       Date:  1990-04       Impact factor: 9.031

9.  Role of inhalation studies with animals in defining human health risks for vehicle and power plant emissions.

Authors:  R O McClellan
Journal:  Environ Health Perspect       Date:  1983-01       Impact factor: 9.031

10.  Two-week, repeated inhalation exposure of F344/N rats and B6C3F1 mice to ferrocene.

Authors:  J D Sun; A R Dahl; N A Gillett; E B Barr; M L Crews; A F Eidson; W E Bechtold; D G Burt; M P Dieter; C H Hobbs
Journal:  Fundam Appl Toxicol       Date:  1991-07
  10 in total

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