Literature DB >> 708877

[Carcinogenicity of orthoaminoazotoluene for mouse intestines].

V I Kaledin, G V Alekseeva, A I Volkova.   

Abstract

Carcinogenic activity of orthoaminoazotoluene in relation to intestinal tissues of A/He mice was revealed. Intestinal tumours developed in 19 of 60 mice given this carcinogen; the tumours were localized in the cecum and represented adenomas and adenocarcinomas secreting mucus.

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Year:  1978        PMID： 708877

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN： 0365-9615


  2 in total

1.  Ortho-aminoazotoluene activates mouse constitutive androstane receptor (mCAR) and increases expression of mCAR target genes.

Authors:  Mariya A Smetanina; Mariya Y Pakharukova; Svitlana M Kurinna; Bingning Dong; Juan P Hernandez; David D Moore; Tatyana I Merkulova
Journal:  Toxicol Appl Pharmacol       Date:  2011-06-06       Impact factor: 4.219

2.  O-aminoazotoluene suppresses hepatocyte proliferation in inbred mice susceptible to hepatocarcinogenesis.

Authors:  A V Eremeev; O A Timofeeva; A V Goloshchapov; S I Il'nitskaya; T I Merkulova; V I Kaledin; N A Setkov
Journal:  Dokl Biol Sci       Date:  2009 Sep-Oct
  2 in total

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