| Literature DB >> 7086843 |
P F Wiley, D W Elrod, D J Houser, F A Richard.
Abstract
Nogalamycin (1) has been modified by changes at C-10 and C-7 and in the dimethylamino group to prepare an extensive series of analogues. The chemistry involved in the modifications and structure--activity relationships among these nogalamycin analogues are discussed, as well as comparisons with previously reported compounds 1, 7-con-O-methylnogarol (2), and disnogamycin (11).Entities:
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Year: 1982 PMID： 7086843 DOI： 10.1021/jm00347a016
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446