Literature DB >> 708575

Oestrogen receptors and the response to endocrine therapy in advanced breast cancer.

M M Roberts, R D Rubens, R J King, R A Hawkins, R R Millis, J L Hayward, A P Forrest.   

Abstract

The relationship between oestrogen-receptor protein (ER) content of the tumour and the response to endocrine therapy was determined in 119 patients, in a collaborative prospective study. Twenty-eight of the 80 patients with measurable ER responded to treatment according to UICC criteria, compared with only 3/39 without ER. It was found that site of biopsy did not influence the result, but tumour content of the tissue sample was significantly related to the presence of receptors. The organizational problems of such a study are discussed.

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Year:  1978        PMID： 708575      PMCID： PMC2009752          DOI： 10.1038/bjc.1978.225

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  5 in total

1.  Comparison of soluble oestrogen and progestin receptor content of primary breast tumours from Japan and Britain.

Authors:  R J King; J L Hayward; S Kumaoka; H Yamamoto
Journal:  Eur J Cancer       Date:  1977-09       Impact factor: 9.162

2.  Pathological review of breast lesions analyzed for estrogen receptor protein.

Authors:  P P Rosen; C J Menendez-Botet; J S Nisselbaum; J A Urban; V Miké; A Fracchia; M K Schwartz
Journal:  Cancer Res       Date:  1975-11       Impact factor: 12.701

3.  A simple method for the determination of oestrogen receptor concentrations in breast tumours and other tissues.

Authors:  R A Hawkins; A Hill; B Freedman
Journal:  Clin Chim Acta       Date:  1975-10-15       Impact factor: 3.786

4.  Measurement of oestradiol receptors by five institutions on common tissue samples.

Authors:  R J King; D M Barnes; R A Hawkins; R E Leake; P V Maynard; M M Roberts
Journal:  Br J Cancer       Date:  1978-09       Impact factor: 7.640

5.  Assessment of response to therapy in advanced breast cancer.

Authors:  J L Hayward; P P Carbone; J C Heusen; S Kumaoka; A Segaloff; R D Rubens
Journal:  Br J Cancer       Date:  1977-03       Impact factor: 7.640
  5 in total
  13 in total

1.  Immunocytochemical reactivity of breast cancer tissue with antibodies to neuron-specific enolase and an adenocarcinoma-associated glycolipid antigen.

Authors:  H Ingelman-Sundberg; B Wikström; N Stormy; P Sundelin; A Hjerpe
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

2.  Cellularity and the quantitation of estrogen receptors.

Authors:  R C Mason; R J Steele; R A Hawkins; W R Miller; A P Forrest
Journal:  Breast Cancer Res Treat       Date:  1982       Impact factor: 4.872

3.  Immunohistochemical studies on oncogene products (EGF-R, c-erbB-2) and growth factors (EGF, TGF-alpha) in human breast cancer: their relationship to oestrogen receptor status, histological grade, mitotic index and nodal status.

Authors:  Y Umekita; N Enokizono; Y Sagara; K Kuriwaki; T Takasaki; A Yoshida; H Yoshida
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

4.  Oestrogen receptor activity in breast cancer detected at a prevalence screening examination.

Authors:  M M Roberts; R A Hawkins; F E Alexander; T J Anderson; R J Steele
Journal:  Breast Cancer Res Treat       Date:  1987-12       Impact factor: 4.872

5.  Oestrogen receptor concentration in primary breast cancer and axillary node metastases.

Authors:  R A Hawkins; R Black; R J Steele; J M Dixon; A P Forrest
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

6.  The relevance of control histology in oestrogen receptor estimation.

Authors:  R J Steele; R A Hawkins; T J Anderson; A P Forrest
Journal:  Br J Cancer       Date:  1987-11       Impact factor: 7.640

7.  Measurement of oestradiol receptors by five institutions on common tissue samples.

Authors:  R J King; D M Barnes; R A Hawkins; R E Leake; P V Maynard; M M Roberts
Journal:  Br J Cancer       Date:  1978-09       Impact factor: 7.640

8.  Epidermal growth factor receptor (EGFr) status associated with failure of primary endocrine therapy in elderly postmenopausal patients with breast cancer.

Authors:  S Nicholson; P Halcrow; J R Sainsbury; B Angus; P Chambers; J R Farndon; A L Harris
Journal:  Br J Cancer       Date:  1988-12       Impact factor: 7.640

9.  Oestrogen-receptor status and sites of metastasis in breast cancer.

Authors:  F C Campbell; R W Blamey; C W Elston; R I Nicholson; K Griffiths; J L Haybittle
Journal:  Br J Cancer       Date:  1981-09       Impact factor: 7.640

10.  Elastosis and response to endocrine therapy in human breast cancer.

Authors:  J R Masters; R R Millis; R J King; R D Rubens
Journal:  Br J Cancer       Date:  1979-05       Impact factor: 7.640
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