Literature DB >> 7085662

Rapid catabolism of 5-fluorouracil in freshly isolated rat hepatocytes as analyzed by high performance liquid chromatography.

J P Sommadossi, D A Gewirtz, R B Diasio, C Aubert, J P Cano, I D Goldman.   

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Year:  1982        PMID： 7085662

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  21 in total

1.  F Nuclear Magnetic Resonance Analysis of 5-Fluorouracil Metabolism in Four Differently Pigmented Strains of Nectria haematococca.

Authors:  D Parisot; M C Malet-Martino; R Martino; P Crasnier
Journal:  Appl Environ Microbiol       Date:  1991-12       Impact factor: 4.792

2.  Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.

Authors:  R B Diasio; T L Beavers; J T Carpenter
Journal:  J Clin Invest       Date:  1988-01       Impact factor: 14.808

3.  Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.

Authors:  X R Pan-Zhou; E Cretton-Scott; X J Zhou; M Y Xie; R Rahmani; R F Schinazi; K Duchin; J P Sommadossi
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

4.  In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.

Authors:  E M Cretton; Z Zhou; L B Kidd; H M McClure; S Kaul; M J Hitchcock; J P Sommadossi
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

5.  Metabolism of 5-fluorouracil to an N-cholyl-2-fluoro-beta-alanine conjugate: previously unrecognized role for bile acids in drug conjugation.

Authors:  D J Sweeny; S Barnes; G D Heggie; R B Diasio
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

6.  Carbon tetrachloride-induced increase in the antitumor activity of cyclophosphamide in mice: a pharmacokinetic study.

Authors:  R N Harris; P J Basseches; P L Appel; A M Durski; G Powis
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

7.  Inhibition of dihydropyrimidine dehydrogenase by alpha-interferon: experimental data on human tumor cell lines.

Authors:  G Milano; J L Fischel; M C Etienne; N Renée; P Formento; A Thyss; M H Gaspard; L Thill; D Cupissol
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

8.  Intestinal 5-fluorouracil absorption: use of Ussing chambers to assess transport and metabolism.

Authors:  P Smith; C Mirabelli; J Fondacaro; F Ryan; J Dent
Journal:  Pharm Res       Date:  1988-09       Impact factor: 4.200

9.  Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys.

Authors:  R F Schinazi; F D Boudinot; S S Ibrahim; C Manning; H M McClure; D C Liotta
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

10.  New approach to metabolism of 5'-deoxy-5-fluorouridine in humans with fluorine-19 NMR.

Authors:  M C Malet-Martino; R Martino; A Lopez; J P Béteille; M Bon; J Bernadou; J P Armand
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333
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