Literature DB >> 708555

Effects of age and sex on ketamine anaesthesia in the rat.

A E Waterman, A Livingston.   

Abstract

Intraperitoneal injections of ketamine 75 mg kg-1 in rats of both sexes (age 1--16 weeks) revealed a significant relationship between increased age and decreased duration of sleeping time for both sexes during the first 3 weeks of age. This decrease in sleeping time seemed to be associated with the increased production of the cyclohexanone oxidation metabolite of ketamine. After 3 weeks of age there was a greater sleeping time in the female rat than the male and this seemed to be associated with a greater ability of the male to produce the cyclohexanone oxidation metabolite.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 708555     DOI： 10.1093/bja/50.9.885

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  8 in total

1.  Sex-dependent changes in ketamine-induced locomotor activity and ketamine pharmacokinetics in preweanling, adolescent, and adult rats.

Authors:  Sanders A McDougall; Ginny I Park; Goretti I Ramirez; Vanessa Gomez; Brittnee C Adame; Cynthia A Crawford
Journal:  Eur Neuropsychopharmacol       Date:  2019-04-10       Impact factor: 4.600

2.  Patient characteristics affect the response to ketamine and opioids during the treatment of vaso-occlusive episode-related pain in sickle cell disease.

Authors:  Raissa Nobrega; Kathy A Sheehy; Caroline Lippold; Amy L Rice; Julia C Finkel; Zenaide M N Quezado
Journal:  Pediatr Res       Date:  2017-09-13       Impact factor: 3.756

3.  Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats.

Authors:  Marie-Chantal Giroux; Pierre Hélie; Patrick Burns; Pascal Vachon
Journal:  Exp Anim       Date:  2015-03-27

4.  Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia.

Authors:  Marie-Chantal Giroux; Raphael Santamaria; Pierre Hélie; Patrick Burns; Francis Beaudry; Pascal Vachon
Journal:  Exp Anim       Date:  2015-10-21

5.  Enhanced fear memories and brain glucose metabolism (18F-FDG-PET) following sub-anesthetic intravenous ketamine infusion in Sprague-Dawley rats.

Authors:  Kennett D Radford; Thomas Y Park; Shalini Jaiswal; Hongna Pan; Andrew Knutsen; Michael Zhang; Mercedes Driscoll; Lisa A Osborne-Smith; Bernard J Dardzinski; Kwang H Choi
Journal:  Transl Psychiatry       Date:  2018-11-30       Impact factor: 6.222

Review 6.  Systematic Review: Anesthetic Protocols and Management as Confounders in Rodent Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging (BOLD fMRI)-Part B: Effects of Anesthetic Agents, Doses and Timing.

Authors:  Aline R Steiner; Frédérik Rousseau-Blass; Aileen Schroeter; Sonja Hartnack; Regula Bettschart-Wolfensberger
Journal:  Animals (Basel)       Date:  2021-01-15       Impact factor: 2.752

7.  Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations.

Authors:  Bernard Lanz; Alireza Abaei; Olivier Braissant; In-Young Choi; Cristina Cudalbu; Pierre-Gilles Henry; Rolf Gruetter; Firat Kara; Kejal Kantarci; Phil Lee; Norbert W Lutz; Małgorzata Marjańska; Vladimír Mlynárik; Volker Rasche; Lijing Xin; Julien Valette
Journal:  NMR Biomed       Date:  2020-08-26       Impact factor: 4.478

8.  Impact of ketamine on learning and memory function, neuronal apoptosis and its potential association with miR-214 and PTEN in adolescent rats.

Authors:  Ji Wang; Min Zhou; Xiaobin Wang; Xiaoling Yang; Maohua Wang; Chunxiang Zhang; Shuzhi Zhou; Ni Tang
Journal:  PLoS One       Date:  2014-06-10       Impact factor: 3.240
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.