Literature DB >> 7083130

Thallium-201-chloride thyroid scintigraphy to evaluate benign and/or malignant nodules: usefulness of the delayed scan.

H Ochi, H Sawa, T Fukuda, Y Inoue, H Nakajima, Y Masuda, T Okamura, Y Onoyama, S Sugano, H Ohkita, Y Tei, K Kamino, Y Kobayashi.   

Abstract

The purpose of this study is to evaluate benign and/or malignant thyroid tumors with 201TI thyroid scan. We studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the 123I thyroid scan. 201TI thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intravenous administration of 1.5-2.0 mCi of 201TI. In 35 (94.6%) of 36 malignant tumors (anaplastic carcinoma, six; papillary carcinoma 23; follicular carcinoma, five; epidermoid carcinoma, one; malignant lymphoma, 1) 201TI accumulated in the cold nodule of the 123I thyroid scan on both early and delayed scans. On the other hand, the delayed 201TI scan was negative in 35 out of 39 (89.7%) benign tumors. Employing early and delayed 201TI scans, we were able to differentiate most malignant thyroid tumors from those which were benign. False-negative and -positive cases are discussed.

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Year:  1982        PMID: 7083130     DOI: 10.1002/1097-0142(19820715)50:2<236::aid-cncr2820500213>3.0.co;2-v

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  20 in total

1.  Diagnosis of malignancy in thyroid nodules by factor analysis of spectral and dynamic structures: a simultaneous dual-isotope dynamic study with thallium-201 and iodine-131.

Authors:  B O Helal; F Frouin; G Schaison; D Leguillouzic; M E Pueyo; R Lebtahi; F Archambaud; A Desgrez; J P Bazin; R Di Paola
Journal:  Eur J Nucl Med       Date:  1992

2.  Early and delayed thallium-201 scintigraphy in thyroid nodules: the relationship between early thallium-201 uptake and perfusion.

Authors:  E Derebek; S Biberoglu; O Kut; S Yesil; S Saydam; M Yilmaz; O Yenici; E Igci; O Gokce; S Canda; A Büyükgebiz; A S Dogan; H Durak
Journal:  Eur J Nucl Med       Date:  1996-05

3.  Computer-assisted radionuclide perfusion study in solitary cold thyroid nodules for diagnosis of malignancy.

Authors:  R Prakash; N Lakshmipathi; A Jena; R V Narayanan; V Behari
Journal:  Eur J Nucl Med       Date:  1985

4.  Diagnostic value of early and delayed 201Tl thyroid scintigraphy in the evaluation of cold nodules for malignancy.

Authors:  E Henze; J Roth; H Boerer; W E Adam
Journal:  Eur J Nucl Med       Date:  1986

5.  Diagnostic value of ultrasonography and TI-201/Tc-99m dual scintigraphy in differentiating between benign and malignant thyroid nodules.

Authors:  Ken Watanabe; Takao Igarashi; Hirokazu Ashida; Sho Ogiwara; Tomoyuki Ohta; Mayuki Uchiyama; Hiroya Ojiri
Journal:  Endocrine       Date:  2018-10-01       Impact factor: 3.633

6.  The role of 201Tl scintigraphy in evaluating proliferative activity in thyroid neoplasms.

Authors:  K Nakada; C Katoh; K Kanegae; E Tsukamoto; K Itoh; M Furudate; N Tamaki
Journal:  Ann Nucl Med       Date:  1996-02       Impact factor: 2.668

7.  The optimum time for tumour imaging with thallium-201.

Authors:  A Sehweil; J H McKillop; G Ziada; M Al-Sayed; H Abdel-Dayem; Y T Omar
Journal:  Eur J Nucl Med       Date:  1988

8.  Thallium-201 scintigraphy in the evaluation of thyroid nodules. A retrospective study of 246 cases.

Authors:  M Koizumi; H Taguchi; M Goto; T Nomura; T Watari
Journal:  Ann Nucl Med       Date:  1993-08       Impact factor: 2.668

9.  Accumulation of thallium-201 in medullary thyroid cancer with negative serum calcitonin and carcinoembryonic antigens: a case report.

Authors:  M Koizumi; T Watari; K Hirabayashi
Journal:  Ann Nucl Med       Date:  1993-02       Impact factor: 2.668

10.  Optimizing dual-time and serial positron emission tomography and single photon emission computed tomography scans for diagnoses and therapy monitoring.

Authors:  Joseph A Thie
Journal:  Mol Imaging Biol       Date:  2007 Nov-Dec       Impact factor: 3.488

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