Literature DB >> 7083068

Antidiuretic effect of acute morphine administration in the conscious rat.

N Wilson, J Ngsee.   

Abstract

Morphine was administered intravenously to normal and to Brattleboro (genetically deficient in antidiuretic hormone) rats. The injection caused a significant decrease in mean arterial pressure and urine flow in all animals, including those homozygous for diabetes insipidus. It is suggested that the antidiuretic effect of morphine may occur independently of ADH release.

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Year:  1982        PMID： 7083068     DOI： 10.1139/y82-031

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN： 0008-4212            Impact factor:   2.273


  3 in total

1.  The effects of N-(cyclopropylmethyl)-19-isopentylnororvinol (M320), a potent agonist at kappa- and mu-opiate receptors, on urine excretion of rats.

Authors:  J M Abrahams; A L Boura; R G Evans; C I Johnston; J E Olley
Journal:  Br J Pharmacol       Date:  1986-12       Impact factor: 8.739

Review 2.  The effects of opioids and opioid analogs on animal and human endocrine systems.

Authors:  Cassidy Vuong; Stan H M Van Uum; Laura E O'Dell; Kabirullah Lutfy; Theodore C Friedman
Journal:  Endocr Rev       Date:  2009-11-10       Impact factor: 19.871

3.  Mechanism of diuretic action of spiradoline (U-62066E)--a kappa opioid receptor agonist in the human.

Authors:  G H Rimoy; N K Bhaskar; D M Wright; P C Rubin
Journal:  Br J Clin Pharmacol       Date:  1991-11       Impact factor: 4.335
  3 in total

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