Literature DB >> 7080956

Influence of nonsteroidal anti-inflammatory compounds on healing of chronic gastric ulcers in rats.

I Szelenyi, H Engler, P Herzog, S Postius, H Vergin, K H Holtermüller.   

Abstract

Pre-treatment with NOSAC led to an increase of ulcer index in a dose-dependent manner indicating the aggravation of gastric lesions under the influence of NOSAC. The severity of mucosal lesions was diminished by lengthening the time between the last day of pre-treatment with NOSAC and the day on which ulcers were induced. When NOSAC were administered after the induction of gastric ulcers, the healing of the latter was significantly delayed.

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Year:  1982        PMID: 7080956     DOI: 10.1007/BF01965139

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  4 in total

1.  The early penetration of experimental gastric ulcers in ra s receiving cortisone.

Authors:  D S KAHN; M J PHILLIPS; S S SKORYNA
Journal:  Am J Pathol       Date:  1961-01       Impact factor: 4.307

2.  A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing.

Authors:  K Takagi; S Okabe; R Saziki
Journal:  Jpn J Pharmacol       Date:  1969-09

3.  Effect of prostaglandin E1 on gastric secretion and ulcer formation in the rat.

Authors:  A Robert; J E Nezamis; J P Phillips
Journal:  Gastroenterology       Date:  1968-10       Impact factor: 22.682

4.  Effects of 15(S)-15-methyl-PGE2 methyl ester on healing of chronic gastric and duodenal ulcers in rats.

Authors:  A Ishibashi; Y Kasuya; K Takeuchi; S Okabe
Journal:  Jpn J Pharmacol       Date:  1979-10
  4 in total
  3 in total

1.  Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms.

Authors:  J H McIntosh; K Byth; D W Piper
Journal:  Gut       Date:  1985-08       Impact factor: 23.059

2.  Effects of misoprostol on delayed ulcer healing induced by aspirin.

Authors:  A G Penney; F J Andrews; P E O'Brien
Journal:  Dig Dis Sci       Date:  1994-05       Impact factor: 3.199

3.  Prostaglandin content in the rat gastric mucosa during healing of chronic ulcers induced by acetic acid.

Authors:  I Szelenyi; S Postius; H Engler
Journal:  Agents Actions       Date:  1983-04
  3 in total

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