Literature DB >> 7080833

A heat-labile necrotic activity in supernatants from cultures of Legionella pneumophila.

B P Berdal, O Olsvik, A A Ogaard.   

Abstract

Crude, concentrated extra-cellular supernatants from Legionella pneumophila produced a soft-tissue necrosis, demonstrated by intraperitoneal or sub-cutaneous injections into infant mice. The reaction was rapid and gave a hemorrhagic tissue necrosis within minutes. Being heat-labile, this tissue reaction is different from those of a heat-stable cytotoxin and a heat-stable hemolysin previously described.

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Year:  1982        PMID: 7080833     DOI: 10.1111/j.1699-0463.1982.tb00100.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Immunol Scand B        ISSN: 0108-0180


  2 in total

1.  Characterization of a Legionella pneumophila extracellular protease exhibiting hemolytic and cytotoxic activities.

Authors:  M G Keen; P S Hoffman
Journal:  Infect Immun       Date:  1989-03       Impact factor: 3.441

Review 2.  Legionnaires disease: historical perspective.

Authors:  W C Winn
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

  2 in total

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