Literature DB >> 7080036

Cytolytic toxins and surface activity.

J H Freer.   

Abstract

Surface-active properties of alpha-toxin and delta-lysin, two cytolytic protein exotoxins of the bacterium Staphylococcus aureus are summarised. The relevance of differences in surface charge density on membranes is discussed in relation to possible mechanisms of binding and membrane penetration by alpha-toxin. An hypothesis for the mechanism of membrane disruption by delta-lysin involving the formation of hydrophilic transmembrane pores is proposed.

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Year:  1982        PMID： 7080036     DOI： 10.1016/0041-0101(82)90204-5

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  8 in total

1.  Pore formation by Staphylococcus aureus alpha-toxin in lipid bilayers. Dependence upon temperature and toxin concentration.

Authors:  G Belmonte; L Cescatti; B Ferrari; T Nicolussi; M Ropele; G Menestrina
Journal:  Eur Biophys J       Date:  1987       Impact factor: 1.733

2.  Ionic channels formed by Staphylococcus aureus alpha-toxin: voltage-dependent inhibition by divalent and trivalent cations.

Authors:  G Menestrina
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

3.  Interaction of tetanus toxin with lipid vesicles. Effects of pH, surface charge, and transmembrane potential on the kinetics of channel formation.

Authors:  G Menestrina; S Forti; F Gambale
Journal:  Biophys J       Date:  1989-03       Impact factor: 4.033

4.  Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles.

Authors:  E Ruhr; H G Sahl
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

5.  Chemical modification of Staphylococcus aureus alpha-toxin by diethylpyrocarbonate: role of histidines in its membrane-damaging properties.

Authors:  C Pederzolli; L Cescatti; G Menestrina
Journal:  J Membr Biol       Date:  1991-01       Impact factor: 1.843

6.  Effect of thiol-activated toxins (streptolysin O, alveolysin, and theta toxin) on the generation of leukotrienes and leukotriene-inducing and -metabolizing enzymes from human polymorphonuclear granulocytes.

Authors:  K D Bremm; W König; P Pfeiffer; I Rauschen; K Theobald; M Thelestam; J E Alouf
Journal:  Infect Immun       Date:  1985-12       Impact factor: 3.441

7.  Generation of leukotrienes from human granulocytes by alveolysin from Bacillus alvei.

Authors:  K D Bremm; H J Brom; J E Alouf; W König; B Spur; A Crea; W Peters
Journal:  Infect Immun       Date:  1984-04       Impact factor: 3.441

8.  Optimizing the Composition of Irrigation Fluid to Reduce the Potency of Staphylococcus aureus α-Toxin: Potential Role in the Treatment of Septic Arthritis.

Authors:  Cheryl L S Liu; Andrew C Hall
Journal:  Cartilage       Date:  2018-09-06       Impact factor: 4.634
  8 in total

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