Literature DB >> 7079769

Tritiated imipramine binding sites are decreased in the frontal cortex of suicides.

M Stanley, J Virgilio, S Gershon.   

Abstract

Binding characteristics of tritiated imipramine were determined in the frontal cortex of suicides and well-matched controls. Maximal binding was significantly lower in brains from the suicides. This finding is consistent with reports of decreased tritiated imipramine binding in the platelets of patients diagnosed as having a major affective disorder.

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Year:  1982        PMID： 7079769     DOI： 10.1126/science.7079769

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  The state of the serotonin transporter protein in the platelets of patients with somatoform [correction of somatiform] disorders.

Authors:  A R Belous; S Ramamoorthy; R D Blakely; M I Factor; A M Dupin; A B Katasonov; R H Lozier; A G Beniashvili; M A Morozova; O S Brusov
Journal:  Neurosci Behav Physiol       Date:  2001 Mar-Apr

2.  Positron emission tomography study of regional brain metabolic responses to a serotonergic challenge in major depressive disorder with and without comorbid lifetime alcohol dependence.

Authors:  Leo Sher; Matthew S Milak; Ramin V Parsey; Juan J Carballo; Thomas B Cooper; Kevin M Malone; Maria A Oquendo; J John Mann
Journal:  Eur Neuropsychopharmacol       Date:  2007-05-02       Impact factor: 4.600

Review 3.  The role of neurotransporters in excitotoxicity, neuronal cell death, and other neurodegenerative processes.

Authors:  K P Lesch; A Heils; P Riederer
Journal:  J Mol Med (Berl)       Date:  1996-07       Impact factor: 4.599

4.  What can post-mortem studies tell us about the pathoetiology of suicide?

Authors:  Ghanshyam N Pandey; Yogesh Dwivedi
Journal:  Future Neurol       Date:  2010-09

Review 5.  Toward a biosignature for suicide.

Authors:  Maria A Oquendo; Gregory M Sullivan; Katherin Sudol; Enrique Baca-Garcia; Barbara H Stanley; M Elizabeth Sublette; J John Mann
Journal:  Am J Psychiatry       Date:  2014-10-31       Impact factor: 18.112

6.  Lower 3H-paroxetine binding in cerebral cortex of suicide victims is partly due to fewer high affinity, non-transporter sites.

Authors:  J J Mann; R A Henteleff; T F Lagattuta; J A Perper; S Li; V Arango
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

7.  Proceedings of the British Pharmacological Society. University of Manchester, 13-15 September 1989.

Authors: 
Journal:  Br J Pharmacol       Date:  1989-12       Impact factor: 8.739

Review 8.  The molecular bases of the suicidal brain.

Authors:  Gustavo Turecki
Journal:  Nat Rev Neurosci       Date:  2014-10-30       Impact factor: 34.870

9.  Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

Authors:  S Ramamoorthy; A L Bauman; K R Moore; H Han; T Yang-Feng; A S Chang; V Ganapathy; R D Blakely
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-15       Impact factor: 11.205

10.  Decreased platelet 3H-imipramine binding sites in classical migraine.

Authors:  D P Geaney; M G Rutterford; J M Elliott; M Schächter; K M Peet; D G Grahame-Smith
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-07       Impact factor: 10.154
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