Literature DB >> 7077350

Anterior horn cell dysfunction in Alzheimer's disease.

M Thomas, J P Ballantyne, S Hansen, A I Weir, D Doyle.   

Abstract

Electrophysiological studies were undertaken on 29 patients with Alzheimer's Disease. A reduction in the number of functioning motor units was found in the extensor digitorum brevis muscle. The electrophysiological parameters of the motor unit potentials were increased compared to control values. Four of seven muscle biopsies showed abnormalities ranging from mild to severe. The results suggest dysfunction in the lower motor neurone in this disease.

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Year:  1982        PMID： 7077350      PMCID： PMC491378          DOI： 10.1136/jnnp.45.4.378

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  8 in total

1.  Axonal dysfunction in the neuropathy of diabetes mellitus: a quantitative electrophysiological study.

Authors:  S Hansen; J P Ballantyne
Journal:  J Neurol Neurosurg Psychiatry       Date:  1977-06       Impact factor: 10.154

2.  A quantitative electrophysiological study of acute idiopathic polyneuritis.

Authors:  A Martinez-Figueroa; S Hansen; J P Ballantyne
Journal:  J Neurol Neurosurg Psychiatry       Date:  1977-02       Impact factor: 10.154

3.  Computer method for the analysis of evoked motor unit potentials. I. Control subjects and patients with myasthenia gravis.

Authors:  J P Ballantyne; S Hansen
Journal:  J Neurol Neurosurg Psychiatry       Date:  1974-11       Impact factor: 10.154

4.  The histographic analysis of human muscle biopsies with regard to fiber types. 2. Diseases of the upper and lower motor neuron.

Authors:  M H Brooke; W K Engel
Journal:  Neurology       Date:  1969-04       Impact factor: 9.910

5.  A quantitative electrophysiological study of motor neurone disease.

Authors:  S Hansen; J P Ballantyne
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-09       Impact factor: 10.154

6.  A quantitative electrophysiological study of uraemic neuropathy. Diabetic and renal neuropathies compared.

Authors:  S Hansen; J P Ballantyne
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-02       Impact factor: 10.154

7.  Quantitative electrophysiological study of alcoholic neuropathy.

Authors:  J P Ballantyne; S Hansen; A Weir; J R Whitehead; P J Mullin
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-05       Impact factor: 10.154

8.  A new method for the estimation of the number of motor units in a muscle. I. Control subjects and patients with myasthenia gravis.

Authors:  J P Ballantyne; S Hansen
Journal:  J Neurol Neurosurg Psychiatry       Date:  1974-08       Impact factor: 10.154
  8 in total
  1 in total

1.  Motor and psychomotor functions in amyotrophic lateral sclerosis evaluated by tests of motor ability.

Authors:  M Poloni; L Mazzini; M Ceroni; P Tosca; G Bezzi
Journal:  Ital J Neurol Sci       Date:  1986-02
  1 in total

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