| Literature DB >> 7076783 |
P Young, M Vaudin, J Dixon, A J Zuckerman.
Abstract
Water-soluble protein micelles consisting of the 28,000 (gp28) and 23,00 (p23) molecular weight polypeptide complex of hepatitis B surface antigen can be readily prepared from human plasma containing the surface antigen and other markers of infection with hepatitis B virus. The antigenic activity of the polypeptides was preserved throughout the process of solubilisation and reassociation into micelles. Such preparations are therefore eminently suitable as "second generation" hepatitis B vaccines.Entities:
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Year: 1982 PMID： 7076783 DOI： 10.1016/0166-0934(82)90046-5
Source DB: PubMed Journal: J Virol Methods ISSN： 0166-0934 Impact factor: 2.014