Literature DB >> 7073990

Globin gene mapping in normal Hb A2 types of beta-thalassaemia.

E Kanavakis, A Metaxotou-Mavromati, C Kattamis, M Aksoy, D J Weatherall, W G Wood.   

Abstract

Globin-gene mapping of DNA from 13 families with normal Hb A2 beta-thalassaemia (both type 1 and type 2) failed to detect any difference from normal in their globin-gene arrangement. We conclude that deletions such as those responsible for gamma beta-thalassaemia or a 'silent' Hb Lepore are not responsible for this type of beta-thalassaemia in Greece.

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Year:  1982        PMID: 7073990     DOI: 10.1111/j.1365-2141.1982.tb07289.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  2 in total

1.  Clinical and haematological evaluation of beta thalassaemia intermedia characterised by unusually low Hb F and increased Hb A2: beta thalassaemia intermedia II.

Authors:  A Gurgey; S Kayin; E Kansu; C Altay
Journal:  J Med Genet       Date:  1985-06       Impact factor: 6.318

2.  Clinical, haematological, and genetic studies of type 2 normal Hb A2 beta thalassaemia.

Authors:  A Metaxotou-Mavromati; C Kattamis; L Matathia; M Tzetis; E Kanavakis
Journal:  J Med Genet       Date:  1988-03       Impact factor: 6.318

  2 in total

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