Literature DB >> 7073969

C1 inhibitor deficiency simulating systemic lupus erythematosus.

S Shiraishi, Y Nara, Y Watanabe, K Matsuda, Y Miki.   

Abstract

A 48-year-old Japanese woman with systemic lupus erythematosus-like lesions of the skin and lips was found to have hereditary angio-oedema. Complement studies revealed low CH50, C1q, C4 and C1 inhibitor levels, with normal C3 and C5 levels. Dramatic clinical improvement followed fresh normal human blood transfusion and systemic betamethasone administration, while the deficient complement component levels were unchanged.

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Year:  1982        PMID: 7073969     DOI: 10.1111/j.1365-2133.1982.tb04540.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  2 in total

Review 1.  Lupus diseases associated with hereditary and acquired deficiencies of complement.

Authors:  V Agnello
Journal:  Springer Semin Immunopathol       Date:  1986

2.  Acquired C1 inhibitor deficiency associated with systemic lupus erythematosus affecting the central nervous system.

Authors:  S Nakamura; M Yoshinari; Y Saku; K Hirakawa; C Miishima; K Murai; K Tokiyama; M Fujishima
Journal:  Ann Rheum Dis       Date:  1991-10       Impact factor: 19.103

  2 in total

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