| Literature DB >> 7073875 |
R N Palmer, C M Kessler, H R Gralnick.
Abstract
Studies of the prothrombin time in normals and patients receiving warfarin therapy revealed a marked shortening of the prothrombin time when the blood was collected in any type of collection tube other than a polypropylene tube. This shortening of the prothrombin time in patients receiving coumadin therapy was time and temperature dependent. This in-vitro shortening of the prothrombin time could lead to serious clinical errors involving dosage of warfarin derivatives to be administered to patients.Entities:
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Year: 1982 PMID： 7073875 DOI： 10.1016/0049-3848(82)90221-3
Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944