Literature DB >> 7073242

[Changes of plasma amino acids in cirrhotics treated with ornithine salts].

R Molimard, C Charpentier, F Lemonnier.   

Abstract

The plasma amino acid pattern of cirrhotic patients was determined before and after 24 h of continuous infusions of glucose, ornithine alpha-ketoglutarate (O alpha KG), ornithine chlorhydrate (ORN HCl) and sodium ketoglutarate (alpha CGNa). Before treatment, leucine, isoleucine, valine and glutamine levels were low. Tyrosine and methionine levels were high. (See formula in text) was low. Glucose infusions had no effect. O alpha KG increased levels of leucine, isoleucine, valine, alanine and arginine. Threonine, serine, glycine, aspartic acid, methionine, hemicystine, tyrosine and phenylalanine were significantly lowered. (See formula in text) increased. ORN HCl and alpha CGNa did not induce similar changes.

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Year:  1982        PMID: 7073242     DOI: 10.1159/000176540

Source DB:  PubMed          Journal:  Ann Nutr Metab        ISSN: 0250-6807            Impact factor:   3.374


  3 in total

1.  Action of ornithine alpha ketoglutarate on DNA synthesis by human fibroblasts.

Authors:  M Vaubourdolle; M Salvucci; C Coudray-Lucas; J Agneray; L Cynober; O G Ekindjian
Journal:  In Vitro Cell Dev Biol       Date:  1990-02

2.  Ornithine alpha-ketoglutarate: could it be a new therapeutic option for sarcopenia?

Authors:  S Walrand
Journal:  J Nutr Health Aging       Date:  2010-08       Impact factor: 4.075

Review 3.  Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy.

Authors:  G Kircheis; M Wettstein; S vom Dahl; D Häussinger
Journal:  Metab Brain Dis       Date:  2002-12       Impact factor: 3.584

  3 in total

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