A case of severe hemolytic disease of the newborn due to anti-Verweyst (Vw).

This report describes a severe case of hemolytic disease of the newborn due to anti-Vw. The Caucasian mother previously had two Vw+ children, neither of whom were affected. The mother had no history of blood transfusion. The cord blood was found to have a positive direct antiglobulin test and the infant required three exchange transfusions.