Literature DB >> 7071455

Characteristics of spindle activity and their use in evaluation of hypnotics.

K Azumi, S Shirakawa.   

Abstract

The spindle activity of 10 healthy male adults, aged 20-24 years, was investigated over 7 consecutive nights. Spindle appearance showed a strikingly distinctive and reproducible pattern for each individual. There was no first-night effect and little night-to-night variation of spindle appearance rate per night. Eight male adults aged between 19 and 24 years were studied in an evaluation of methaqualone and flunitrazepam by an experimental schedule of 17 consecutive nights. Both drugs caused a significant increase of spindle activity expressed as appearance rate. By using spindle activity as a sleep parameter we could investigate in more detail the characteristics of hypnotics.

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Year:  1982        PMID： 7071455     DOI： 10.1093/sleep/5.1.95

Source DB:  PubMed          Journal:  Sleep        ISSN： 0161-8105            Impact factor:   5.849


  9 in total

Review 1.  Polysomnographic effects of hypnotic drugs. A review.

Authors:  L Parrino; M G Terzano
Journal:  Psychopharmacology (Berl)       Date:  1996-07       Impact factor: 4.530

2.  Effects of oral temazepam on sleep spindles during non-rapid eye movement sleep: A high-density EEG investigation.

Authors:  D T Plante; M R Goldstein; J D Cook; R Smith; B A Riedner; M E Rumble; L Jelenchick; A Roth; G Tononi; R M Benca; M J Peterson
Journal:  Eur Neuropsychopharmacol       Date:  2015-07-02       Impact factor: 4.600

3.  Genetic evidence for a role for protein kinase A in the maintenance of sleep and thalamocortical oscillations.

Authors:  Kevin Hellman; Pepe Hernandez; Alice Park; Ted Abel
Journal:  Sleep       Date:  2010-01       Impact factor: 5.849

Review 4.  About sleep's role in memory.

Authors:  Björn Rasch; Jan Born
Journal:  Physiol Rev       Date:  2013-04       Impact factor: 37.312

5.  Sleep in a sitting position: effect of triazolam on sleep stages and EEG power spectra.

Authors:  D Aeschbach; C Cajochen; I Tobler; D J Dijk; A A Borbély
Journal:  Psychopharmacology (Berl)       Date:  1994-03       Impact factor: 4.530

6.  Alprazolam-induced EEG spectral power changes in rhesus monkeys: a translational model for the evaluation of the behavioral effects of benzodiazepines.

Authors:  Lais F Berro; John S Overton; Jaren A Reeves-Darby; James K Rowlett
Journal:  Psychopharmacology (Berl)       Date:  2021-02-16       Impact factor: 4.530

7.  Characterizing sleep spindles in 11,630 individuals from the National Sleep Research Resource.

Authors:  S M Purcell; D S Manoach; C Demanuele; B E Cade; S Mariani; R Cox; G Panagiotaropoulou; R Saxena; J Q Pan; J W Smoller; S Redline; R Stickgold
Journal:  Nat Commun       Date:  2017-06-26       Impact factor: 14.919

8.  Can People Sleep Too Much? Effects of Extended Sleep Opportunity on Sleep Duration and Timing.

Authors:  Elizabeth B Klerman; Giuseppe Barbato; Charles A Czeisler; Thomas A Wehr
Journal:  Front Physiol       Date:  2021-12-22       Impact factor: 4.755

9.  Ongoing network state controls the length of sleep spindles via inhibitory activity.

Authors:  Péter Barthó; Andrea Slézia; Ferenc Mátyás; Lejla Faradzs-Zade; István Ulbert; Kenneth D Harris; László Acsády
Journal:  Neuron       Date:  2014-06-18       Impact factor: 17.173
  9 in total

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