Literature DB >> 7070580

The effect of phentolamine on synaptosomal phosphatidylinositol in experimental galactose toxicity.

G Berry, J R Yandrasitz, S Segal.   

Abstract

Abnormal myo-[2-3H]inositol incorporation into phosphatidylinositol has been found in phentolamine-treated synaptosomes that were isolated from the cerebral hemispheres of galactose toxic rats and incubated with [33P]Pi and myo-[2-3H] inositol. In galactose toxic rats phentolamine-stimulated myo-[2-3H]inositol labeling of phosphatidylinositol was 70% greater than in normal animals. This enhanced labeling of synaptosomal phosphatidylinositol in galactose toxic rats during stimulation with phentolamine is in marked contrast to the depressed myo-inositol labeling of phosphatidylinositol reported with acetylcholine stimulation.

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Year:  1982        PMID： 7070580     DOI： 10.1007/bf00965068

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  12 in total

Review 1.  Inositol phospholipids and cell surface receptor function.

Authors:  R H Michell
Journal:  Biochim Biophys Acta       Date:  1975-03-25

2.  Identification of cytidine diphosphate-diglyceride in the pineal gland of the rat and its accumulation in the presence of DL-propranolol.

Authors:  G Hauser; J Eichberg
Journal:  J Biol Chem       Date:  1975-01-10       Impact factor: 5.157

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Letter: The redirection of glyceride and phospholipid synthesis by drugs including chlorpromazine, fenfluramine, imipramine, mepyramine and local anaesthetics.

Authors:  D N Brindley; D Allan; R H Michell
Journal:  J Pharm Pharmacol       Date:  1975-06       Impact factor: 3.765

5.  A sensitive and specific method for the measurement of monophosphoinositide at a microregional level in brain.

Authors:  T J Cicero; W R Sherman
Journal:  Anal Biochem       Date:  1973-07       Impact factor: 3.365

6.  d-Galactose transport by synaptosomes isolated from rat brain.

Authors:  A S Warfield; S Segal
Journal:  J Neurochem       Date:  1974-12       Impact factor: 5.372

7.  The effect of MnCl2 on the basal and acetylcholine-stimulated turnover of phosphatidylinositol in synaptosomes.

Authors:  J R Yandrasitz; S Segal
Journal:  FEBS Lett       Date:  1979-12-01       Impact factor: 4.124

8.  De novo glycerolipid biosynthesis in the toad and cattle retina. Redirecting of the pathway by propranolol and phentolamine.

Authors:  N G Bazán; M G De Boschero; N M Giusto; H E De Bazán
Journal:  Adv Exp Med Biol       Date:  1976       Impact factor: 2.622

Review 9.  Significance of minor glycerolipids in membrane structure and function.

Authors:  R H Michell; D Allan; J B Finean
Journal:  Adv Exp Med Biol       Date:  1976       Impact factor: 2.622

10.  Experimental galactose toxicity: effects on synaptosomal phosphatidylinositol metabolism.

Authors:  G Berry; J R Yandrasitz; S Segal
Journal:  J Neurochem       Date:  1981-10       Impact factor: 5.372
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