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Literature DB >> 7069744

Effect of exercise on serum creatine kinase in carriers of Duchenne muscular dystrophy.

R F Gaines, S M Pueschel, E A Sassaman, J L Driscoll.

Abstract

In order to evaluate the effect of exercise on serum creatine kinase levels, blood samples were obtained from 17 normal females and 12 Duchenne muscular dystrophy carriers before and 9 hours after moderately strenuous exercise. The results revealed that after exercise serum creatine kinase levels may be better indicators of carrier status than resting levels. The mean serum creatine kinase levels before and after exercise, as well as the mean increases, were found to be significantly greater in Duchenne muscular dystrophy carriers than in normal control subjects.

Entities: Disease

Mesh：

Substances：
Creatine Kinase

Year: 1982 PMID： 7069744 PMCID： PMC1048811 DOI： 10.1136/jmg.19.1.4

Source DB: PubMed Journal: J Med Genet ISSN： 0022-2593 Impact factor: 6.318

21 in total

1. An improved procedure for serum creatine phosphokinase determination.

Authors: S B Rosalki
Journal: J Lab Clin Med Date: 1967-04

2. A possible role for electron microscopy in detection of carriers of Duchenne type muscular dystrophy.

Authors: A K Afifi; R A Bergman; H Zellweger
Journal: J Neurol Neurosurg Psychiatry Date: 1973-08 Impact factor: 10.154

3. Changes in serum creatine phosphokinase during submaximal exercise testing.

Authors: J R Ledwich
Journal: Can Med Assoc J Date: 1973-08-18 Impact factor: 8.262

4. Identification of carriers of Duchenne muscular dystrophy by muscle protein synthesis.

Authors: V Ionasescu; H Zellweger; P Shirk; T W Conway
Journal: Neurology Date: 1973-05 Impact factor: 9.910

5. Variability of serum creatine phosphokinase activity in normal women and carriers of the gene for Duchenne muscular dystrophy.

Authors: T B Perry; F C Fraser
Journal: Neurology Date: 1973-12 Impact factor: 9.910

6. Creatine kinase and glutamic oxalacetic transaminase activity in serum: kinetics of change with exercise and effect of physical conditioning.

Authors: F Q Nuttall; B Jones
Journal: J Lab Clin Med Date: 1968-05

7. Studies of the carrier state in the Duchenne type of muscular dystrophy. 2. Quantitative electromyography as a method of carrier detection.

Authors: D Gardner-Medwin
Journal: J Neurol Neurosurg Psychiatry Date: 1968-04 Impact factor: 10.154

Effect of exercise on serum creatine kinase in carriers of Duchenne muscular dystrophy.

1. An improved procedure for serum creatine phosphokinase determination.

2. A possible role for electron microscopy in detection of carriers of Duchenne type muscular dystrophy.

3. Changes in serum creatine phosphokinase during submaximal exercise testing.

4. Identification of carriers of Duchenne muscular dystrophy by muscle protein synthesis.

5. Variability of serum creatine phosphokinase activity in normal women and carriers of the gene for Duchenne muscular dystrophy.

6. Creatine kinase and glutamic oxalacetic transaminase activity in serum: kinetics of change with exercise and effect of physical conditioning.

7. Studies of the carrier state in the Duchenne type of muscular dystrophy. 2. Quantitative electromyography as a method of carrier detection.

8. Serum enzymes after marathon running.

9. Serum creatine kinase studies in the detection of carriers of Duchenne dystrophy.

10. Abnormalities of the electrocardiogram in female carriers of Duchenne muscular dystrophy.

Review 1. Duchenne muscular dystrophy: pathogenetic aspects and genetic prevention.

Review 2. Effect of exercise on serum enzyme activities in humans.

3. Persistent HyperCKemia in Athletes.

4. Loss of membrane integrity drives myofiber death in lipin1-deficient skeletal muscle.