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Literature DB >> 7068920

Intracellular immunoglobulin distribution of bone marrow plasma cells as a diagnostic aid for primary amyloidosis.

C Thielemans, W Aelbrecht, D Verbeelen, G Somers, M De Waele, B Van Camp.

Abstract

In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal proliferation of light chain containing plasma cells, and thus led to the diagnosis of immunoglobulin-related amyloidosis.

Entities: Disease Species

Mesh：

Substances：

Year: 1982 PMID： 7068920 PMCID： PMC497530 DOI： 10.1136/jcp.35.3.285

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

16 in total

1. Immunoglobulins and amyloidosis. An immunologic study of sixty-two patients with biopsy-proved disease.

Authors: E S Cathcart; R F Ritchie; A S Cohen; K Brandt
Journal: Am J Med Date: 1972-01 Impact factor: 4.965

Review 2. Amyloidosis: its nature and pathogenesis.

Authors: G G Glenner; W D Terry; C Isersky
Journal: Semin Hematol Date: 1973-01 Impact factor: 3.851

3. An immunofluorescence study on intracellular immunoglobulins in human bone marrow cells.

Authors: W Hijmans; H R Schuit; E Hulsing-Hesselink
Journal: Ann N Y Acad Sci Date: 1971-06-21 Impact factor: 5.691

4. An immunofluorescence procedure for the detection of intracellular immunoglobulins.

Authors: W Hijmans; H R Schuit; F Klein
Journal: Clin Exp Immunol Date: 1969-04 Impact factor: 4.330

5. Structural identity of Bence Jones and amyloid fibril proteins in a patient with plasma cell dyscrasia and amyloidosis.

Authors: W D Terry; D L Page; S Kimura; T Isobe; E F Osserman; G G Glenner
Journal: J Clin Invest Date: 1973-05 Impact factor: 14.808

6. Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors: G Mancini; A O Carbonara; J F Heremans
Journal: Immunochemistry Date: 1965-09

7. Light chain typing of immunoglobulins in small samples of biological material.

Authors: J Rádl
Journal: Immunology Date: 1970-07 Impact factor: 7.397

8. Patterns of amyloidosis and their association with plasma-cell dyscrasia, monoclonal immunoglobulins and Bence-Jones proteins.

Authors: T Isobe; E F Osserman
Journal: N Engl J Med Date: 1974-02-28 Impact factor: 91.245