| Literature DB >> 7068605 |
S P Damle, L Cöster, J D Gregory.
Abstract
The major proteoglycan of pig skin, a proteodermatan sulfate, has been isolated under mild conditions in the presence of protease inhibitors. After purification by ion exchange and gel chromatography, it has a Mr of 70 x 10(3) and it does not form aggregates with hyaluronic acid. It contains about 60% protein, one chain of dermatan sulfate, and several oligosaccharide chains. The dermatan sulfate is high in iduronic acid (85% of the uronic acid) and there are no chains of chondroitin sulfate present. The oligosaccharides contain glucosamine, sialic acid, and neutral sugars.Entities:
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Year: 1982 PMID： 7068605
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157