Bone involvement in hairy-cell leukemia.

Destructive bone involvement is a rarely recognized complication of hairy-cell leukemia (leukemic reticuloendotheliosis). We report a case in which localized hip pain and lytic bone lesions were the presenting manifestations. A second case of bone involvement in a patient with previously diagnosed hairy-cell leukemia is also described. These cases are compared with the nine cases of hairy-cell leukemia with bone involvement previously published in the medical literature.