| Literature DB >> 7066384 |
M V Mikhaĭlov, A S Zasedatelev, G V Gurskiĭ.
Abstract
Experimental studies are reported on the binding of actinomycin D to various synthetic and naturally occurring DNAs. The experimental data obtained agree with a model in which the antibiotic molecule carries only one GC-specific reaction center and covers 5 base pairs upon binding to DNA. Positive cooperative effects are observed for the binding of actinomycin to poly(dG-dC)-poly (dG-dC) duplex.Entities:
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Year: 1982 PMID： 7066384
Source DB: PubMed Journal: Biofizika ISSN： 0006-3029