| Literature DB >> 7066140 |
M Weinstock, J T Davidson, A J Rosin, H Schnieden.
Abstract
The effects of physostigmine 1 mg i.v. were studied on the analgesia, sedation and reduction in respiratory rate induced by morphine 10 mg/60 kg i.v. in 10 patients recovering from surgery. Within 5-10 min, physostigmine abolished the somnolent effect of morphine and restored the respiratory rate to pre-drug values. Analgesia, assessed by an independent observer and by the patient was, if anything, increased by physostigmine. The analeptic effect of physostigmine lasted 40-60 min.Entities:
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Year: 1982 PMID： 7066140 DOI： 10.1093/bja/54.4.429
Source DB: PubMed Journal: Br J Anaesth ISSN： 0007-0912 Impact factor: 9.166