| Literature DB >> 7066033 |
J Sany, J Clot, M Bonneau, M Andary.
Abstract
Patients who had active and severe rheumatoid arthritis (RA) were treated with human placenta-eluted gamma globulins (PEGG) composed of purified IgG eluted from trophoblastic cells. A control group of RA patients received retroplacental gamma globulins with no clinical effects. Seven of eleven treatments with PEGG showed good (4 patients) or very good (3 patients) clinical results. All patients had immunologic modifications demonstrated by a significant increase in active E-rosette-forming cells and mitogen responsiveness. The precise mechanism of immunomodulating effect of PEGG should be further investigated.Entities:
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Year: 1982 PMID： 7066033 DOI： 10.1002/art.1780250103
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591