Literature DB >> 7065059

Noncontraceptive health benefits of oral steroidal contraceptives.

D R Mishell.   

Abstract

Prospective and retrospective epidemiologic studies involving oral contraceptives have been reviewed to determine the existence and extent of their benefits other than prevention of pregnancy. There is less menstrual blood loss, which reduces the risk of iron deficiency anemia by about 50%. The incidence of menorrhagia, irregular menses, and intermenstrual bleeding is also significantly reduced in users of oral contraceptives. Studies have shown an approximate 50% reduction in risk of endometrial cancer in oral contraceptive users, as well as a significant reduction in various types of benign breast disease. Because oral contraceptives inhibit ovulation, functional ovarian cysts are nearly eliminated, and the incidence of dysmenorrhea and premenstrual tension is significantly reduced. Oral contraceptives also protect women from developing ovarian carcinoma, rheumatoid arthritis, and salpingitis. From this review we conclude that the benefits of oral contraceptives in young healthy women for far outweight their more widely publicized, infrequent risks.

Entities:  

Keywords:  Adnexitis; Biology; Cancer; Contraception; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Contraceptive Mode Of Action; Diseases; Endometrial Cancer; Endometrial Effects; Epidemiologic Methods; Family Planning; Infections; Literature Review; Luteinizing Hormone; Mammary Gland Effects; Menstruation; Menstruation Disorders; Neoplasms; Ovarian Cancer; Ovulation Suppression; Pelvic Inflammatory Disease; Physiology; Prospective Studies; Reproduction; Reproductive Tract Infections; Research Methodology; Retrospective Studies; Studies

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Year:  1982        PMID: 7065059     DOI: 10.1016/s0002-9378(16)32492-9

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  7 in total

Review 1.  Noncontraceptive health benefits of oral contraceptives.

Authors:  Andrew M Kaunitz
Journal:  Rev Endocr Metab Disord       Date:  2002-09       Impact factor: 6.514

2.  Associations between recent contraceptive use and quality of life among women.

Authors:  Sanithia L Williams; Sara M Parisi; Rachel Hess; E Bimla Schwarz
Journal:  Contraception       Date:  2011-09-19       Impact factor: 3.375

3.  Systemic effects of oral contraceptives.

Authors:  T M Kelly
Journal:  West J Med       Date:  1984-07

Review 4.  Contraceptive choice for women with 'risk factors'.

Authors:  I S Fraser
Journal:  Drug Saf       Date:  1993-04       Impact factor: 5.606

5.  Pregnancy and rheumatic disease. A review of recent studies in rheumatoid arthritis and ankylosing spondylitis.

Authors:  M Ostensen; G Husby
Journal:  Klin Wochenschr       Date:  1984-10-01

Review 6.  Risk-benefit assessment of drugs used for the treatment of menstrual disorders.

Authors:  J M Higham; R W Shaw
Journal:  Drug Saf       Date:  1991 May-Jun       Impact factor: 5.606

Review 7.  Benefits and risks of pharmacological agents used for the treatment of menorrhagia.

Authors:  Samendra Nath Roy; Siladitya Bhattacharya
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

  7 in total

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