Literature DB >> 7061649

Determination of gamma-aminobutyric acid by liquid chromatography with electrochemical detection.

W L Caudill, G P Houck, R M Wightman.   

Abstract

gamma-Aminobutyric acid (GABA) has been determined in rat brain by derivatization with 2,4,6-trinitrobenzenesulfonic acid. The derivative and an internal standard, 2,4,6-trinitrophenyl-delta-aminovaleric acid, are extracted into toluene and separated by reversed-phase chromatography. Electrochemical reduction of these derivatives permits picomole measurements of GABA in microgram amounts of brain tissue.

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Year:  1982        PMID： 7061649     DOI： 10.1016/s0378-4347(00)80387-4

Source DB:  PubMed          Journal:  J Chromatogr


  6 in total

1.  Electrochemical detection of human brain transmitter amino acids by high-performance liquid chromatography of stable o-phthalaldehyde-sulphite derivatives.

Authors:  S J Pearson; C Czudek; K Mercer; G P Reynolds
Journal:  J Neural Transm Gen Sect       Date:  1991

2.  Brain-Implantable Multifunctional Probe for Simultaneous Detection of Glutamate and GABA Neurotransmitters.

Authors:  Nicolaie Moldovan; Iuliu-Ioan Blaga; Sanjeev Billa; Imran Hossain; Chenggong Gong; Claire E Jones; Teresa A Murray; Ralu Divan; Shabnam Siddiqui; Prabhu U Arumugam
Journal:  Sens Actuators B Chem       Date:  2021-03-15       Impact factor: 9.221

3.  Comparison of release of endogenous dopamine and gamma-aminobutyric acid from rat caudate synaptosomes.

Authors:  W L Caudill; J C Bigelow; R M Wightman
Journal:  Neurochem Res       Date:  1985-03       Impact factor: 3.996

4.  Gabapentin augments whole blood serotonin in healthy young men.

Authors:  M L Rao; P Clarenbach; M Vahlensieck; S Krätzschmar
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

5.  A Novel Microbiosensor Microarray for Continuous ex Vivo Monitoring of Gamma-Aminobutyric Acid in Real-Time.

Authors:  Imran Hossain; Chao Tan; Phillip T Doughty; Gaurab Dutta; Teresa A Murray; Shabnam Siddiqui; Leonidas Iasemidis; Prabhu U Arumugam
Journal:  Front Neurosci       Date:  2018-08-07       Impact factor: 4.677

6.  Brain-Implantable Multifunctional Probe for Simultaneous Detection of Glutamate and GABA Neurotransmitters: Optimization and In Vivo Studies.

Authors:  Sanjeev Billa; Yaswanthi Yanamadala; Imran Hossain; Shabnam Siddiqui; Nicolaie Moldovan; Teresa A Murray; Prabhu U Arumugam
Journal:  Micromachines (Basel)       Date:  2022-06-26       Impact factor: 3.523
  6 in total

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