| Literature DB >> 7059420 |
D M Chambers, G C Jefferson, M Chambers, N B Loudon.
Abstract
1 A 'low-dose' combined oral contraceptive steroid (OCS) preparation containing 30 microgram ethinylo-estradiol and 150 microgram levonorgestrel was found to reduce significantly antipyrine clearance in a group of women acting as their own controls. 2 An OCS preparation containing only a progestogen (75 microgram norgestrel) did not reduce antipyrine clearance in a second group of women. 3 The evidence suggesting that the oestrogen component of combined OCS preparations could be responsible for the reduction in antipyrine clearance is discussed.Entities:
Keywords: Biology; Comparative Studies; Contraception; Contraceptive Agents; Contraceptive Agents, Estrogen; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Endocrine System; Estrogens; Ethinyl Estradiol; Family Planning; Hormones; Levonorgestrel; Literature Review; Norgestrel; Oral Contraceptives; Oral Contraceptives, Combined; Oral Contraceptives, Low-dose; Physiology; Research Methodology; Studies
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Year: 1982 PMID： 7059420 PMCID： PMC1401993 DOI： 10.1111/j.1365-2125.1982.tb01362.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335