Literature DB >> 705871

A safe blood transfusion procedure for immunization against major histocompatibility complex determinants in man.

G B Ferrara, R Tosi, A Longo, A Castellani, C Viviani, G Carminati.   

Abstract

A standardized procedure is proposed for deliberate immunizations against human major histocompatibility complex determinants. The data presented demonstrate its effectiveness and, by using a number of necessary precautions, this procedure has proven to be very safe. The following points are especially important: (1) exclusive utilization of regular blood donors as immunizers; (3) use of whole blood as an immunizing agent; and (3) use of small immunizing stimuli rather than large transfusions. This procedure can be recommended for the production of monospecific anti-HLA antisera and it may be useful if and when a deliberate transfusion policy for prospective kidney recipients is adopted.

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Year:  1978        PMID： 705871     DOI： 10.1097/00007890-197809000-00003

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   4.939


  8 in total

1.  Serological discrimination of DR4 haplotypes by radioimmunoassay.

Authors:  N Tanigaki; R Tosi; G B Ferrara
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

2.  Serological recognition of HLA-DR allodeterminant corresponding to DNA sequence involved in gene conversion.

Authors:  C C Berte; N Tanigaki; R Tosi; J Gorski; B Mach
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

3.  Immunochemistry of the HLA class II molecules isolated from a mouse cell transfected with DQ alpha and beta genes from a DR4 haplotype.

Authors:  N Tanigaki; R Tosi; J L Strominger; J Cooper
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

4.  Human Ia molecules carrying DC1 or BR4X7 determinants are not homologous to murine I-E molecules.

Authors:  R Tosi; N Tanigaki; R Sorrentino; P van Mourik; P Ivanyi
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

5.  Human lymphoblastoid cell lines secreting antibodies with restricted HLA specificity.

Authors:  M P Pistillo; N Tanigaki; O Mazzoleni; E Ciccone; U Hämmerling; M Park; P I Terasaki; G B Ferrara
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

6.  The distribution of DR5, MT2, and MB3 specificities on human Ia subsets.

Authors:  N Tanigaki; R Tosi; K Sagawa; J Minowada; G B Ferrara
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

7.  Molecular identification of human Ia antigens coded for by a gene locus closely linked to HLA-DR locus.

Authors:  N Tanigaki; R Tosi; D Pressman; G B Ferrara
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

8.  Immunological dissection of human Ia molecules.

Authors:  R Tosi; N Tanigaki; D Centis; G B Ferrara; D Pressman
Journal:  J Exp Med       Date:  1978-12-01       Impact factor: 14.307
  8 in total

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