| Literature DB >> 7057052 |
N Levine, L Queen, A A Chalom, L J Daniels.
Abstract
An animal model which allows for the implantation and development of intracutaneous melanoma is described. Intradermal vesicles are created by a negative pressure apparatus in DBA/2J mice. S91 melanoma cells are injected into the blister cavities. Tumor growth occurs within 7 days and the yield approaches 100%. This model is a rapid, efficient, and applicable system for the study of melanoma growth dynamics and of the effects of systemic and topical anti-tumor agents on melanoma proliferation.Entities:
Mesh：
Year: 1982 PMID： 7057052 DOI： 10.1111/1523-1747.ep12506432
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551