Literature DB >> 7056353

The effect of cholinergic antagonists on a central response to nicotine.

L S Schwab, M F Kritzer.   

Abstract

Mecamylamine and hexamethonium antagonize the prostration response of rats to centrally-administered nicotine; decamethonium and d-tubocurarine are less effective. physostigmine does not elicit the response. Nicotine's central cholinergic effect thus may contribute to but does not fully account for its action.

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Year:  1982        PMID： 7056353     DOI： 10.1007/bf01944563

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Acute and chronic effects of nicotine in rats and evidence for a noncholinergic site of action.

Authors:  L G Abood; K Lowy; H Booth
Journal:  NIDA Res Monogr       Date:  1979-01

2.  Electrophysiological, behavioral, and chemical evidence for a noncholinergic, stereospecific site for nicotine in rat brain.

Authors:  L G Abood; K Lowy; A Tometsko; H Booth
Journal:  J Neurosci Res       Date:  1978       Impact factor: 4.164

3.  Stereospecific nicotine receptors on rat brain membranes.

Authors:  C Romano; A Goldstein
Journal:  Science       Date:  1980-11-07       Impact factor: 47.728

4.  Stereospecific 3H-nicotine binding to intact and solubilized rat brain membranes and evidence for its noncholinergic nature.

Authors:  L G Abood; D T Reynolds; J M Bidlack
Journal:  Life Sci       Date:  1980-10-06       Impact factor: 5.037

5.  Evidence for a noncholinergic site for nicotine's action in brain: psychopharmacological, electrophysiological and receptor binding studies.

Authors:  L G Abood; K Lowy; A Tometsko; M MacNeil
Journal:  Arch Int Pharmacodyn Ther       Date:  1979-02

6.  Barrel rotation induced by vasopressin and related peptides in rats.

Authors:  H Kruse; T B Van Wimersma Greidanus; D De Wied
Journal:  Pharmacol Biochem Behav       Date:  1977-10       Impact factor: 3.533
  6 in total
  1 in total

1.  Discriminative stimulus properties of nicotine: further evidence for mediation at a cholinergic receptor.

Authors:  J A Pratt; I P Stolerman; H S Garcha; V Giardini; C Feyerabend
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
  1 in total

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