Literature DB >> 7056162

[The place of lymphoscintigraphy in the treatment of malignant melanoma of the skin (author's transl)].

D L Munz, P Altmeyer, H Holzmann, A Encke, G Hör.   

Abstract

Lymphoscintigraphy was performed pre- or postoperatively in 42 patients with malignant melanoma of the skin. The test consisted of the injection of 1.5-2.0 mCi 99mTc-labelled antimony sulphide colloid, both intracutaneously and subcutaneously, either around the primary tumour or along its edges or into the centre of the excision scar or contralaterally. The draining lymph-node groups were scanned with a gamma-camera 4-6 hours after the injection. Except for one patient, the radioactive tracer had always disappeared from the injection site and had accumulated in th regional lymph-nodes. In 11 of 28 patients with melanoma on the trunk, lymphatic drainage was to more than one regional lymph-node group. In most cases with cutaneous melanoma on the trunk, lymphatic drainage could not be anatomically predicted, but easily and unequivocally identified by lymphoscintigraphy. On the other hand, lymphatic drainage of a melanoma of the head or neck, as well as of distal segments of the limbs, almost always followed anatomical expectations. Using lymphoscintigraphic findings, prophylactic lymphadenectomy could be performed selectively in "high risk" melanomas.

Entities:  

Mesh:

Substances:

Year:  1982        PMID: 7056162     DOI: 10.1055/s-2008-1069877

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  2 in total

1.  Lymphoscintigraphy in the detection of cervical metastases from oral carcinoma: a pilot study.

Authors:  R Sri-Pathmanathan; R Railton
Journal:  Ann R Coll Surg Engl       Date:  1989-09       Impact factor: 1.891

2.  Scintigraphy of lymphatic vessels in malignant melanoma of the skin before operation (en bloc excision).

Authors:  K Buchali; H Winter; H J Blesin; M Schürer; K Sydow
Journal:  Eur J Nucl Med       Date:  1985
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.