Literature DB >> 7055393

The role of antibiotic bonding in the prevention of vascular prosthetic infections.

R S Greco, R A Harvey.   

Abstract

Oxacillin, a negatively charged antibiotic, was bonded to polytetrafluoroethylene (PTFE) grafts using the cationic surfactant, benzalkonium chloride. Control PTFE grafts and bonded grafts prepared at room temperature and at 90 C were placed in the infrarenal aorta of dogs and challenged by local contamination with Staphylococcus aureus. Bonded grafts were superior to controls in negative cultures, patency, and survival. The possible role of antibiotic bonding in the prevention of vascular prosthetic infection is discussed.

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Year:  1982        PMID： 7055393      PMCID： PMC1352437          DOI： 10.1097/00000658-198202000-00008

Source DB:  PubMed          Journal:  Ann Surg        ISSN： 0003-4932            Impact factor:   12.969


  6 in total

1.  Studies of a graphite-benzalkonium-oxacillin surface.

Authors:  R Jagpal; R S Greco
Journal:  Am Surg       Date:  1979-12       Impact factor: 0.688

2.  Antibiotic bonding to vascular prostheses.

Authors:  R Henry; R A Harvey; R S Greco
Journal:  J Thorac Cardiovasc Surg       Date:  1981-08       Impact factor: 5.209

3.  The noncovalent bonding of antibiotics to a polytetrafluoroethylene-benzalkonium graft.

Authors:  R A Harvey; R S Greco
Journal:  Ann Surg       Date:  1981-11       Impact factor: 12.969

4.  Prosthetic arterial graft material. Influence on neointimal healing and bacteremic infectibility.

Authors:  W S Moore; J M Malone; K Keown
Journal:  Arch Surg       Date:  1980-11

5.  Diffusion of antibiotics from a polytetrafluoroethylene-benzalkonium surface.

Authors:  A Prahlad; R A Harvey; R S Greco
Journal:  Am Surg       Date:  1981-12       Impact factor: 0.688

6.  Antibiotic prophylaxis in vascular surgery.

Authors:  A B Kaiser; K R Clayson; J L Mulherin; A C Roach; T R Allen; W H Edwards; W A Dale
Journal:  Ann Surg       Date:  1978-09       Impact factor: 12.969
  6 in total
  5 in total

1.  Catheter-Related Bloodstream Infection.

Authors: 
Journal:  Curr Infect Dis Rep       Date:  1999-08       Impact factor: 3.725

Review 2.  Review of general surgery 1982.

Authors:  H Ellis
Journal:  Postgrad Med J       Date:  1983-07       Impact factor: 2.401

3.  Stability of antibiotics bound to polytetrafluoroethylene with cationic surfactants.

Authors:  A P Donetz; R A Harvey; R S Greco
Journal:  J Clin Microbiol       Date:  1984-01       Impact factor: 5.948

4.  Efficacy of dicloxacillin-coated polyurethane catheters in preventing subcutaneous Staphylococcus aureus infection in mice.

Authors:  R J Sherertz; D M Forman; D D Solomon
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

5.  Antibiotic concentrations in the groin wound after vascular prosthetic implantation.

Authors:  A C Van Loenen; H J Martens; A J Mackaay; J A Rauwerda; F C Bakker; G A Vos
Journal:  Pharm Weekbl Sci       Date:  1991-08-23
  5 in total

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