Literature DB >> 7054311

Antipruritic effect of an opiate antagonist, naloxone hydrochloride.

J E Bernstein, R M Swift, K Soltani, A L Lorincz.   

Abstract

Central elicitation of itch by morphine may result from binding to opiate receptors, mimicking the physiological binding of endorphins and enkephalins to these receptors. Pretreatment of normal subjects with naloxone hydrochloride resulted in diminution or abolition of histamine-provoked itch. These results suggest an important role for central opioid peptides as mediators of the itch sensation.

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Year:  1982        PMID： 7054311     DOI： 10.1111/1523-1747.ep12497974

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  9 in total

1.  Clinical Features and Drug Treatment of Psychodermatological Disorders.

Authors:  M Van Moffaert
Journal:  CNS Drugs       Date:  1994-03       Impact factor: 5.749

Review 2.  Mouse models of acute, chemical itch and pain in humans.

Authors:  Robert H LaMotte; Steven G Shimada; Parul Sikand
Journal:  Exp Dermatol       Date:  2011-10       Impact factor: 3.960

3.  [Antipruritic therapy with the oral opioid receptor antagonist naltrexone. Open, non-placebo controlled administration in 133 patients].

Authors:  A Brune; D Metze; T A Luger; S Ständer
Journal:  Hautarzt       Date:  2004-12       Impact factor: 0.751

Review 4.  Pruritus: a practical approach.

Authors:  P J Greco; J Ende
Journal:  J Gen Intern Med       Date:  1992 May-Jun       Impact factor: 5.128

5.  Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice.

Authors:  K Kasutani; E Fujii; S Ohyama; H Adachi; M Hasegawa; H Kitamura; N Yamashita
Journal:  Br J Pharmacol       Date:  2014-09-05       Impact factor: 8.739

Review 6.  Recent advances in the management of pruritus in chronic liver diseases.

Authors:  Kazuto Tajiri; Yukihiro Shimizu
Journal:  World J Gastroenterol       Date:  2017-05-21       Impact factor: 5.742

7.  Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model.

Authors:  Masanori Fujii; Sayaka Ohgami; Erika Asano; Takanori Nakayama; Takahiro Toda; Takeshi Nabe; Susumu Ohya
Journal:  Sci Rep       Date:  2019-02-20       Impact factor: 4.379

Review 8.  Cholestasis-Associated Pruritus and Its Pruritogens.

Authors:  Jacqueline A G M Langedijk; Ulrich H Beuers; Ronald P J Oude Elferink
Journal:  Front Med (Lausanne)       Date:  2021-03-09

9.  Effect of nalfurafine hydrochloride in patients with chronic liver disease with refractory pruritus on sleep disorders: a study protocol for single-arm, prospective, interventional study.

Authors:  Kazunori Yoh; Hiroki Nishikawa; Hirayuki Enomoto; Yoshinori Iwata; Akio Ishii; Yukihisa Yuri; Noriko Ishii; Yuho Miyamoto; Kunihiro Hasegawa; Chikage Nakano; Ryo Takata; Takashi Nishimura; Nobuhiro Aizawa; Yoshiyuki Sakai; Naoto Ikeda; Tomoyuki Takashima; Hiroko Iijima; Shuhei Nishiguchi
Journal:  BMJ Open Gastroenterol       Date:  2017-09-29
  9 in total

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