Literature DB >> 7053582

Iodine-125-labeled triiodothyronine in rat brain: evidence for localization in discrete neural systems.

M B Dratman, Y Futaesaku, F L Crutchfield, N Berman, B Payne, M Sar, W E Stumpf.   

Abstract

Autoradiograms prepared from adult rat brains demonstrate that nerve cells and neuropil in different brain regions selectively concentrate and retain intravenously administered triiodothyronine, by mechanisms susceptible to saturation with excess triiodothyronine. A neuroregulatory role for thyroid hormones, strongly supported by the observations, may account for their marked effects on behavior and the activity of the autonomic nervous system.

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Year:  1982        PMID： 7053582     DOI： 10.1126/science.7053582

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  3-Monoiodothyronamine: the rationale for its action as an endogenous adrenergic-blocking neuromodulator.

Authors:  Heinrich S Gompf; Joel H Greenberg; Gary Aston-Jones; Alexandra G Ianculescu; Tom S Scanlan; Mary B Dratman
Journal:  Brain Res       Date:  2010-07-23       Impact factor: 3.252

2.  Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine.

Authors:  Alexandra G Ianculescu; Edith C H Friesema; Theo J Visser; Kathleen M Giacomini; Thomas S Scanlan
Journal:  Mol Biosyst       Date:  2010-03-31

3.  Thyroid stimulating hormone and cognition during severe, transient hypothyroidism.

Authors:  Frank V Schraml; Pamela W Goslar; Leslie Baxter; Lori L Beason-Held
Journal:  Neuro Endocrinol Lett       Date:  2011       Impact factor: 0.765

4.  Regional distribution of nuclear T3 receptors in rat brain and evidence for preferential localization in neurons.

Authors:  J Ruel; R Faure; J H Dussault
Journal:  J Endocrinol Invest       Date:  1985-08       Impact factor: 4.256

5.  Effects of acute microinjections of the thyroid hormone derivative 3-iodothyronamine to the preoptic region of adult male rats on sleep, thermoregulation and motor activity.

Authors:  Thomas D James; Steven X Moffett; Thomas S Scanlan; Joseph V Martin
Journal:  Horm Behav       Date:  2013-05-20       Impact factor: 3.587

6.  Intrathecal triiodothyronine administration causes greater heart rate stimulation in hypothyroid rats than intravenously delivered hormone. Evidence for a central nervous system site of thyroid hormone action.

Authors:  M Goldman; M B Dratman; F L Crutchfield; A S Jennings; J A Maruniak; R Gibbons
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

7.  Interactions of L-3,5,3'-Triiodothyronine [corrected], Allopregnanolone, and Ivermectin with the GABAA Receptor: Evidence for Overlapping Intersubunit Binding Modes.

Authors:  Thomas Westergard; Reza Salari; Joseph V Martin; Grace Brannigan
Journal:  PLoS One       Date:  2015-09-30       Impact factor: 3.240

Review 8.  Update on 3-iodothyronamine and its neurological and metabolic actions.

Authors:  Riccardo Zucchi; Alice Accorroni; Grazia Chiellini
Journal:  Front Physiol       Date:  2014-10-16       Impact factor: 4.566

9.  L-3,3',5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors.

Authors:  Steven X Moffett; Eric A Klein; Grace Brannigan; Joseph V Martin
Journal:  PLoS One       Date:  2019-10-04       Impact factor: 3.240
  9 in total

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