Long-term follow-up of patients with malformations for which definitive surgical repair has been available for 25 years or more.

The results of long-term follow-up studies of patients with five common congenital heart defects are reviewed. The lesions included are ventricular septal defect, atrial septal defect, patent ductus arteriosus, pulmonary stenosis and coarctation of the aorta. A definitive, rather than palliative, operation has been available for each of these lesions for more than 25 years. Therefore many patients who have undergone operation for one of these lesions are now reaching adulthood. Although most of these postoperative patients live a normal life, many have residuae or sequelae that require close observation or treatment. Other persistent abnormalities of the physical examination, electrocardiogram and chest radiogram are obvious but call for no precaution or treatment. We have drawn on our own experience and the published experience of others to identify those findings and historical factors that best reflect the long-term prognosis of these patients. In addition, recommendations concerning the need for continued prophylaxis against infective endocarditis, and the problems of insurability and employability of these postoperative patients are discussed.