Literature DB >> 7050382

Metabolic activation and drug toxicity.

S D Nelson.   

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Year:  1982        PMID: 7050382     DOI: 10.1021/jm00349a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  17 in total

Review 1.  Metabolism of clozapine by neutrophils. Possible implications for clozapine-induced agranulocytosis.

Authors:  J P Uetrecht
Journal:  Drug Saf       Date:  1992       Impact factor: 5.606

2.  Formation of reactive 1-nitropyrene metabolites by lung microsomes and isolated lung cells.

Authors:  E Dybing; J E Dahl; F A Beland; S S Thorgeirsson
Journal:  Cell Biol Toxicol       Date:  1986-09       Impact factor: 6.691

3.  Differences in N-acetylation of the experimental antitumor agent batracylin in the mouse and the rat.

Authors:  M M Ames; D A Mathiesen; J M Reid
Journal:  Invest New Drugs       Date:  1991-08       Impact factor: 3.850

4.  The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites.

Authors:  H S Purba; J L Maggs; M L Orme; D J Back; B K Park
Journal:  Br J Clin Pharmacol       Date:  1987-04       Impact factor: 4.335

5.  Antifungal triazole alcohols: a comparative analysis of structure-activity, structure-teratogenicity and structure-therapeutic index relationships using the Multiple Computer-Automated Structure Evaluation (Multi-CASE) methodology.

Authors:  G Klopman; D Ptchelintsev
Journal:  J Comput Aided Mol Des       Date:  1993-06       Impact factor: 3.686

6.  Irreversible binding of tolmetin glucuronic acid esters to albumin in vitro.

Authors:  A Munafo; A F McDonagh; P C Smith; L Z Benet
Journal:  Pharm Res       Date:  1990-01       Impact factor: 4.200

7.  Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity.

Authors:  D W Roberts; T J Bucci; R W Benson; A R Warbritton; T A McRae; N R Pumford; J A Hinson
Journal:  Am J Pathol       Date:  1991-02       Impact factor: 4.307

8.  BIOTRANSFORMATION OF HYDRAZINE DERVATIVES IN THE MECHANISM OF TOXICITY.

Authors:  Birandra K Sinha; Ronald P Mason
Journal:  J Drug Metab Toxicol       Date:  2014-07-08

Review 9.  Put a ring on it: application of small aliphatic rings in medicinal chemistry.

Authors:  Matthias R Bauer; Paolo Di Fruscia; Simon C C Lucas; Iacovos N Michaelides; Jennifer E Nelson; R Ian Storer; Benjamin C Whitehurst
Journal:  RSC Med Chem       Date:  2021-01-07

10.  Development of matrix metalloproteinase-13 inhibitors - A structure-activity/structure-property relationship study.

Authors:  Rita Fuerst; Jun Yong Choi; Anna M Knapinska; Lyndsay Smith; Michael D Cameron; Claudia Ruiz; Gregg B Fields; William R Roush
Journal:  Bioorg Med Chem       Date:  2018-08-20       Impact factor: 3.641

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